Sponsor Deadline
Posted: 4/17/2025

Environmental Health Sciences Core Centers (EHSCC) (P30 Clinical Trial Optional)

This Notice of Funding Opportunity (NOFO) invites grant applications for Environmental Health Sciences Core Centers (EHSCC). As intellectual hubs for environmental health science research, the EHSCC are expected to be the thought leaders for the field and advance the goals of the 2025-2029 NIEHS Strategic Plan (http://www.niehs.nih.gov/about/strategicplan/). The Core Centers provide critical research infrastructure, shared facilities, services and/or resources, to groups of investigators conducting environmental health sciences research.  An EHSCC enables researchers to conduct their independently-funded individual and/or collaborative research projects more efficiently and/or more effectively. The overall goal of an EHSCC is to identify and capitalize on emerging issues that advance improving the understanding of the relationships among environmental exposures, human biology, and disease.  The EHSCC supports community engagement and translational research as key approaches to improving public health.

This Notice of Funding Opportunity (NOFO) requires a Plan for Enhancing Diverse Perspectives (PEDP).

Only one application per Institution is allowed. Interested applicants from within Duke should contact fundopps@duke.edu as early as possible.

Deadlines:

  • Letter of Intent Due Date: Feb. 17, 2025
  • Application Due Date(s): March 18, 2025; Jan. 30, 2026; Jan. 29, 2027

RFA-ES-22-010 Expiration Date January 30, 2027

Eligibility Requirements

To be eligible for an EHSCC award, the applicant institution must demonstrate that four or more Center members have combined grant funding of at least $3 million per year in direct costs. At the time of submission of an application, the qualifying awards must have at least 1 full active year remaining. These projects must be Environmental Health Sciences focused, related to the NIEHS Mission and 2025-2029 NIEHS Strategic Plan, and address environmental exposures and health. These may be a mix of NIH, Federal and privately funded awards or career development awards. However, at least 50% of the research base must be from the NIH.

Examples of NIH peer-reviewed mechanisms that may be included for determining eligibility: DP1, DP2, R00, R01, R03, R15, R21, R24, R25, R33, R35, R37, R41, R42, R43, R44, P01, P20, P30s other than the EHSCC, P42, P50, SC1, SC2, U01, U10, U19, U24, U54, U56, UH2, UH3, UG3, K and F series awards.

T-awards, U45, and Conference awards (R13, U13) do not count towards this requirement. Furthermore, grants and cooperative agreements in extension periods, either with or without additional funds, as well as supplements of any kind, do not count toward this requirement. 

Amount Description

New or first-time applicants are limited to $850,000 Direct Costs per year. Renewal applications are limited to $1.0M Direct Costs per year. See Eligibility requirements.

New or first-time applicants may apply for up to 4 years of support. Renewal applications may request up to 5 years of support.