Establishing a Cohort to Clarify Risk and Protective Factors for Neurocognitive Complications of Pediatric Type 1 Diabetes (T1D) - Planning Cooperative Agreements (U34 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

This FOA invites applications for planning cooperative agreements (U34) for a national, multisite, observational cohort study to prospectively examine the risk and protective factors for neurocognitive complications of pediatric type 1 diabetes (T1D; onset approximately ages 5-10 years) and a comparison sample. The U34 is designed to: 1) Permit early peer review of the rationale for the proposed cohort study; 2) Permit assessment of the study design; and 3) Provide support for the development of essential elements required for the design and conduct of the cohort study and the management and analysis of the study data. Consultation with NIDDK scientific staff is strongly encouraged prior to the submission of the U34 application.


  • Letter of Intent Due Date(s): March 11, 2019
  • Application Due Date(s): April 11, 2019

RFA-DK-18-007 Expiration April 12, 2019

Agency Website



Amount Description

Budgets for direct costs of up to $225,000 per year are allowed. The funds requested are expected to vary based on the number of clinical centers involved in the study and the complexity of the study.
The scope of the proposed project should determine the project period. The maximum project period is 2 years.

Funding Type





Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

April 11, 2019