Explainable Artificial Intelligence for Decoding and Modulating Neural Circuit Activity Linked to Behavior (R01 Clinical Trial Optional)

Funding Agency:
National Institutes of Health

Explainable Artificial Intelligence (XAI) aims to provide strong predictive value along with mechanistic understanding of AI by combining machine learning techniques with effective explanatory techniques. This Funding Opportunity Announcement (FOA) solicits applications in the area of XAI applied to neuroscientific questions of encoding, decoding, and modulation of neural circuits linked to behavior. This FOA encourages collaborations between computationally and experimentally-focused investigators. This FOA seeks the development of machine learning algorithms that are able to mechanistically explain how experimental manipulations affect cognitive, affective, or social processing in humans or animals. Proof-of-concept applications aimed at improving the current state of the technology that uses XAI to provide unbiased, hierarchical explanations of causal relationships between complex neural and behavioral data are also appropriate .


  • Letter of Intent Due Date(s): 30 days prior to the application due date
  • Application Due Date(s): March 10, 2020, March 10, 2021, March 10, 2022

PAR-19-344 Expiration Date March 11, 2022




Engineering and Physical Sciences
Medical - Basic Science
Medical - Translational

External Deadline

March 10, 2020