Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations (Collaborative U01 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) seeks applications proposing coordinated efforts to accelerate gene discovery for psychiatric disorders in cohorts of non European ancestry to advance the important goal of global mental health discovery and equity. This funding opportunity announcement (FOA) is one of several FOAs supporting a program called, “Ending Disparities in Mental Health” (EDIfy-MH).

Specifically, this FOA seeks to support the genetic and clinical characterization of subjects with highly-heritable severe mental illness (e.g., schizophrenia, autism and bipolar disorder) in global populations of African ancestry on the African continent for the purpose of enhancing efforts to fine-map genetic risk loci across the allelic spectrum.

This FOA should be used when two or more collaborating sites are essential to conduct the proposed research. It is required that the Research Strategy be identical across linked collaborative U01 applications, with the exception of a short section describing the specific function of each application under "elements unique to this site." The Human Subjects section for each application should be specific to the research conducted at that site. For a linked set of collaborative U01 applications, each application must have its own Program Director/Principal Investigator (PD/PI) and the program must provide a mechanism for cross-site coordination. Applications from a single-site should be submitted under the companion FOA ( PAR-20-026 ).

Deadlines:

  • Letter of Intent: January 15, 2020
  • Application Due Date(s): February 14, 2020, September 15, 2020, September 15, 2021

PAR-20-027 Expiration Date New Date September 16, 2021 per issuance of NOT-MH-21-016. (Original Expiration Date: September 16, 2022 )

Agency Website

Eligibility Requirements

This FOA only accepts applications that are part of a collaborative set of multiple applications. A set must contain at least 2  applications.

Funding Type

Grant

Eligibility

Faculty

Category

Environmental & Life Sciences
International Opportunities
Medical
Medical - Basic Science
Medical - Clinical Science

External Deadline

September 15, 2021