Genetic Engineering Technologies for HIV Cure Research (U19 Clinical Trial Optional)

Funding Agency:
National Institutes of Health

The purpose of this Funding Opportunity Announcement (FOA) is to apply genetic engineering technologies to HIV-1 cure research.  Gene- and/or cell-based approaches are sought that can achieve long-term remission of HIV-1 in the absence of antiretroviral treatment or complete elimination of HIV-1.  Applications are expected to include basic science/preclinical research as well as translational activities such as test-of-concept studies in animal models or human subjects and must be designed as collaborative efforts between academia and the private sector.


  • Letter of Intent Due Date(s): February 11, 2019
  • AIDS Application Due Date(s): March 11, 2019

RFA-AI-18-058 Expiration Date March 12, 2019

Agency Website



Amount Description

Application budgets are limited to $1.75 million in direct costs per year. Budgets should reflect the actual needs of the proposed project.

The scope of the proposed project should determine the project period. The maximum project period is 5 years.

Funding Type





Engineering and Physical Sciences
Environmental & Life Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

March 11, 2019