Sponsor Deadline
Posted: 12/18/2023

HEAL Initiative: Development and Validation of Non-Rodent Mammalian Models of Pain (R01 Clinical Trial Not Allowed)

This funding opportunity announcement (FOA) invites research to develop, characterize, and rigorously validate non-rodent mammalian models of pain, associated outcome measures and/or endpoints that will significantly advance translational research for effective pain management. These models are expected to recapitulate molecular, cellular, pathological, behavioral, and/or cognitive aspects of human pain disorders and conditions. Research supported under this FOA is expected to provide well-validated models and measures that facilitate the development of non-opioid analgesic therapeutic interventions with little or no addiction liability.


  • Letter of Intent Due Date(s): 30 days prior to the application due date.

  • Application Due Dates: Nov 4, 2022; March 7, 2023; July 6, 2023; Nov 7, 2023; March 6, 2024

RFA-NS-22-070 Expiration Date March 07, 2024

Amount Description

Application budgets need to reflect the actual needs of the proposed project and are limited to direct costs of $750,000 per year.

The scope of the proposed project should determine the project period. The maximum project period is 5 years.

Funding Type