The purpose of this NIH Mentored Research Scientist Development Award (K01) is to provide salary and research support to investigators who are within ten years of completing their terminal professional degree or residency training. Research and mentorship must be in the field of HIV/AIDS translational studies, using nonhuman primates (NHPs) as preclinical models. These awards will provide 3 years of support for intensive research career development under the guidance of an experienced mentorship team, with expertise in both the pre-clinical application of NHP HIV/AIDS models and in translation of the results from such studies to clinical application in humans. The expectation is that this sustained experience will launch independent research careers and enable awardees to become competitive for new research project grant (e.g., R01) funding. This funding initiative addresses research priorities of the fiscal year (FY) 2021-2025 NIH Strategic Plan for HIV and HIV-Related Research (https://www.oar.nih.gov/hiv-policy-and-research/strategic-plan): reduce the incidence of HIV; develop next-generation HIV therapies; research toward HIV cure; and address HIV-associated comorbidities, coinfections, and complications.
This Notice of Opportunity Announcement (NOFO) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Applicants to this NOFO are permitted to propose research experience in a clinical trial led by a mentor and/or co-mentor.
Research with NHPs incurs unusually high costs due to the enhanced care, handling and longevity of the animals. Therefore, candidates are strongly encouraged to concurrently submit a scientifically distinct application in response to the companion R21 Notice of Funding Opportunity PAR-23-215 (ORIP, NIMH) to acquire additional funds to support the NHP research. Additionally, K award recipients are encouraged to obtain funding from NIH or other Federal sources either as a PD/PI on a competing research grant award or cooperative agreement, or as project leader on a competing multi-project award as described in NOT-OD-08-065.
AIDS Application Due Date(s): Jan. 7, May 7, Sep. 7
PAR-23-225Expiration Date September 08, 2025
Multiple PDs/PIs are not allowed.
By the time of award, the individual must be a citizen or a non-citizen national of the United States or have been lawfully admitted for permanent residence (i.e., possess a currently valid Permanent Resident Card USCIS Form I-551, or other legal verification of such status).
Professors, Associate Professors or equivalent, regardless of grant history, are not eligible.
Candidates for this award must have a research or health-professional doctoral degree, must have completed at least two years of postdoctoral training or equivalent and must be within 10 years of their terminal professional degree or residency at the time of application, whichever date is later. The candidate must be an Assistant Professor, Assistant Scientist, Research Assistant Professor, or equivalent. The candidate should have an appointment at an institution that includes an NHP facility, such as a National Primate Research Center or similar, which can provide NHPs, core facilities and intellectual resources for using NHPs in HIV/AIDS research. If exceptionally well justified, the candidate can have a primary appointment at an institution distinct from that which houses the NHP-related facilities and infrastructure. However, all work directly related to animals must be performed at the institution that houses the NHP-related facilities and related infrastructure.
Current and former PDs/PIs on NIH research project (R01), program project (P01), center grants (P50), Project Leads of program project (P01), or center grants (P50), other major individual career development awards (e.g., K01, K07, K08, K22, K23, K25, K76, K99/R00), or the equivalent are not eligible. Current and former PDs/PIs of an NIH Small Grant (R03), Exploratory/Developmental Grants (R21/R33), Planning Grant (R34/U34), Dissertation Award (R36), or SBIR/STTR (R41, R42, R43, R44) remain eligible, as do PD/PIs of Transition Scholar (K38) awards and individuals appointed to institutional K programs (K12, KL2).
Candidates for the K01 award must have a research or health-professional doctoral degree.
This funding opportunity may support individuals who propose to train in a new field or individuals who have had a hiatus in their research career because of illness or pressing family circumstances.
See full solicitation for details.