IBD Plexus: Academic Request for Proposals

Funding Agency:
Crohns & Colitis Foundation of America

IBD Plexus was founded by the Foundation to advance science, accelerate progress towards precision medicine, and improve the care of patients living with IBD. This first-of-its kind, national-scale, cloud-based platform integrates clinical, patient-reported, genetic, and other molecular data from diverse research study cohorts, real-world clinical care settings, and patients’ experiences. IBD Plexus provides academic and industry researchers with access to research-ready datasets and biosamples to more rapidly perform activities that promise to speed treatment development, optimize existing therapies through development of biomarkers and diagnostics, and improve health outcomes. 

The Crohn’s & Colitis Foundation is excited to release an international request for proposals (RFP) for academic researchers to gain access to IBD patients’ biosamples and / or research-ready datasets housed within IBD Plexus®. The Foundation seeks research proposals that would utilize IBD Plexus biosamples and / or data to facilitate efforts in 4 main areas: 1) identification and / or validation of diagnostics / biomarkers, 2) therapeutic development and optimization 3) disease management 4) disease prevention

This is a rolling solicitation. The Foundation will continue to accept responses to the RFP until all awards are distributed.

Agency Website

Areas of Interest

The goal of IBD Plexus is to accelerate research in high impact areas. The Foundation seeks research proposals that would utilize IBD Plexus biosamples and / or data to drive progress towards precision medicine and / or leverage real world data to produce real world evidence. Priority will be given to proposals that enable answering one or more of the following main areas: 

1) identification and / or validation of diagnostics / biomarkers, 

2) therapeutic development and optimization, 

3) disease management, and

4) disease prevention 

Eligibility Requirements

The lead principal investigator (PI) must be an investigator (e.g. Professor, Head of Research, Associate Professor, or equivalent) with expertise in a relevant field of research. At the time of application, PI and any co-PIs must be employed by an institution (public non-profit, private non-profit, or government) engaged in health care and/or health care related research. Proposals involving multiple institutions are welcome.

Funding Type





Medical - Basic Science
Medical - Clinical Science
Medical - Translational