Implementation of Findings from PCORI's Research Investments -- Cycle 1 2024

Funding Agency:
Patient-Centered Outcomes Research Institute

The Patient-Centered Outcomes Research Institute (PCORI) intends to release a PCORI Funding Announcement (PFA)* on January 9, 2024, seeking to fund implementation projects that promote the uptake of peer-reviewed findings from specific, high-priority, PCORI-funded patient-centered comparative clinical effectiveness research (CER) in the context of the body of related evidence. This PFA is an open competition opportunity for principal investigators to propose implementation projects that move evidence toward practical use in improving health care and health outcomes. Applicants may propose projects with budgets up to $2.5 million in total direct costs. 

Letter of Intent Deadline: Feb. 6, 2024

Agency Website

Areas of Interest

While this PFA is an open competition, PCORI has interest only in applications proposing projects to implement specific PCORI-funded evidence identified by PCORI. Each release of this PFA will identify as the focus of implementation selected published, peer-reviewed evidence. 

Note that the evidence selected as the focus for implementation may change from cycle to cycle. 

For the Cycle 1 2024 PFA, PCORI has identified the following four areas of eligible evidence: 

  1. Obesity treatment in primary care settings.  

  2. Nonsurgical treatment options can improve or eliminate symptoms for women with urinary incontinence (UI). 

  3. Several kinds of therapy and medicines can reduce or stop symptoms for people with posttraumatic stress disorder (PTSD).

  4. The use of narrow-spectrum versus broad-spectrum antibiotics to treat children’s acute respiratory tract infections (ARTIs). 

Funding Type





Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

February 6, 2024