Improving Delivery of HIV Prevention and Treatment through Implementation Science and Translational Research (R01, R21)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) encourages research designed to increase the public health impact of efficacious HIV/AIDS-related interventions for prevention and treatment. To maximize the public health impact of available interventions, significant progress is needed to advance science designed to get interventions to the men, women, and children who need them. The goals of this scientific agenda are to learn how best to deliver interventions more efficiently and effectively in real-world communities and clinics, to more readily transfer interventions from one setting or population to another, and to make better-informed choices for combination intervention packages.

Although this funding opportunity uses the R01 mechanism, it runs in parallel with a program announcement of identical scope, PA-14-129, which uses the R21 grant mechanism. The R21 mechanism is specifically intended to encourage new exploratory and developmental research projects. These studies should break new ground or extend previous discoveries toward new directions or applications. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel methodologies, tools, technologies, or interventions that could have a major impact on health research and practice. Unlike applications under the R01 mechanism, preliminary data are not required for R21 applications. Preliminary data may nonetheless be included if available. 

AIDS Application Due Date(s): Jan. 7, May 7, Sep. 7

PA-14-129 Expiration Date January 8, 2017

Agency Website



Amount Description

Budget for direct costs are limited to $275,000 over an R21 two-year period, with no more than $200,000 direct costs allowed in any single year. Applicants may request direct costs in $25,000 modules, up to the total direct costs limitation of $275,000 for the combined two-year award period.  

Funding Type





Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

January 7, 2017