Improving Outcomes for Pediatric, Adolescent and Young Adult Cancer Survivors (U01 Clinical Trial Required)

Funding Agency:
National Institutes of Health

Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) will stimulate the scientific development of effective, feasible, and scalable interventions to address adverse physical and psychosocial effects in survivors of pediatric and/or adolescent/young adult (AYA) cancers.  These interventions may be delivered by providers, communities, and/or healthcare systems.

This FOA is associated with the Childhood Cancer Survivorship, Treatment, Access, and Research (STAR) Act of 2018 that is intended to maximize and accelerate discovery, development, and availability of promising childhood cancer treatments. This FOA is also associated with the Beau Biden Cancer MoonshotSM Initiative that is intended to accelerate cancer research in general.

This FOA requests applications from investigators to develop and test interventions that prevent, mitigate or manage adverse outcomes in pediatric and/or AYA cancer survivors and/or evaluate models of care that strengthen coordination, continuity, and quality, or that reduce access barriers to needed services including follow-up care, and that improve outcomes across the survivor's lifespan. Development of interventions to address disparities in outcomes and/or access to needed care, and to address the needs of minority or medically underserved pediatric and/or AYA populations is of high priority.  


  • Letter of Intent Due Date(s): February 15, 2019; December 3, 2019
  • Application Due Date(s): March 15, 2019; January 3, 2020

RFA-CA-19-033 Expiration Date January 4, 2020

Agency Website

Eligibility Requirements

All individuals designated as PD(s)/PI(s) should have demonstrated expertise in

  • cancer survivor research and/or
  • pediatric and/or AYA cancer expertise.



Amount Description

Application budget needs to reflect the actual needs of the proposed project but must not exceed $500,000 (direct costs) per year.

The scope of the proposed project should determine the project period. The maximum project period is 5 years. 

Funding Type





Medical - Clinical Science
Social Sciences

External Deadline

January 3, 2020