This notice of funding opportunity (NOFO) aims to support research programs that adopt innovative scalable technologies to inventory, register and molecularly profile distributed cell ensembles encoding the effects of addictive substances, across various stages of exposure (acute, chronic, withdrawal, abstinence, relapse). Emphasis is on approaches capable of integrating data generated through population-scale measurements of cellular activity dynamics in behaving rodents, with other granular data modalities, collected from the same cells at single-cell resolution, such as transcriptomic class, epigenetic state, connectivity and spatial localization. The overarching goal is to inform new models for the mechanisms whereby cells are recruited into neuronal ensembles to encode addiction-associated neurobehavioral states.
Deadlines:
-
Letter of Intent Due Date(s):30 days prior to application due date
-
Application Due Date(s): Feb. 21, 2024; Feb. 20, 2025; Feb. 23, 2026
RFA-DA-25-023 Expiration Date February 24, 2026
Applications may not request more than $700,000 direct costs for any one year.
The maximum project period is 5 years.