Integrative Research on Polysubstance Abuse and Disorder (R61/R33 Clinical Trial Optional)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) is supported by Collaborative Research on Addiction (CRAN) at the National Institutes of Health (NIH), a trans-NIH partnership composed of the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Institute on Drug Abuse (NIDA), and the National Cancer Institute (NCI). The intent of this FOA is two-fold: (1) characterize how the neurobiological alterations, associated behaviors, and public health consequences arising from polysubstance use differ from, or are similar to, those observed in single drug use; (2) promote integrative polysubstance research along a translational pipeline, consisting of basic science research in animals, human-based laboratory investigations, and epidemiological studies. These dual objectives will be accomplished with an Exploratory/Developmental Phased Award (R61/R33) mechanism, where polysubstance research can occur in any of these translational stages during the R61 phase and these findings will be rapidly back- or forward-integrated into another stage during the R33 phase, permitting accelerated bi-directional research exchange.

Deadlines:

  • Letter of Intent Due Date(s): 30 days prior to the application due date
  • Application Due Dates: March 17, 2020, July 17, 2020, November 17, 2020, March 17, 2021, July 19, 2021, November 17, 2021, March 17, 2022, July 19, 2022, November 7, 2022
  • AIDS Due Dates: March 17, 2020, July 17, 2020, November 17, 2020, March 17, 2021, July 19, 2021, November 17, 2021, March 17, 2022, July 19, 2022, November 7, 2022

​PAR-20-035 Expiration Date November 8, 2022

Agency Website

Amount Description

Application direct costs are limited to $300,000 during each year of the R61 phase and $500,000 during each year of the R33 phase.

 The project period is limited to 2 years for the R61 phase and up to 3 years for the R33 phase. The total project period may not exceed 5 years.  

    Funding Type

    Grant

    Eligibility

    Faculty

    Category

    Medical
    Medical - Basic Science
    Medical - Clinical Science
    Medical - Translational

    External Deadline

    November 7, 2022