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The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional)
The purpose of this Funding Opportunity Announcement (FOA) is to invite R01 applications on the influence and intersection of sex and gender in health and disease, including: (1) research applications that examine sex and gender factors and their intersection in understanding health and disease; and (2) research that addresses one of the five objectives from Strategic Goal 1 of the 2019-2023 Trans-NIH Strategic Plan for Women's Health Research "Advancing Science for the Health of Women." The awards under this FOA will be administered by NIH ICs using funds that have been made available through the Office of Research on Women’s Health (ORWH) and the scientific partnering Institutes and Centers across NIH.
- Letter of Intent Due Date(s): 30 days prior to the application due date
- Application Due Date(s): Dec. 19, 2022; Nov 22, 2023; Nov 22, 2024
RFA-OD-22-028 Expiration Date:November 23, 2024
Areas of Interest
This FOA supports basic, preclinical, translational and clinical research investigations composed of teams who share expertise, knowledge, and skills in the following research formats:
Interdisciplinary or transdisciplinary research that includes collaborations across a range of disciplines, including but not limited to, economics, medical anthropology, psychology, and demography to address research from a multi-disciplinary perspective that may address gaps in the fuller context of women's lives and the underlying common root causes of poorer health outcomes.
In addition to new, cross-cutting interdisciplinary research, studies that leverage existing funded cohorts and datasets for analyses of hypotheses related to sex and gender influences in health and disease are of high interest. Comparative analyses of existing samples/datasets/databases and/or data-mining and data curation to investigate the role of sex/gender are encouraged.
This FOA is designed to stimulate research that incorporates and/or enhances understanding of the influence of sex and gender and their intersectionality in health outcomes. For further information on NIH's expectations about consideration of sex as a biological variable, and NIH's initiative to improve reproducibility through rigor and transparency, please see the following Notices published in the NIH Guide: NOT-OD-15-102, NOT-OD-15-103, NOT-OD-16-011, NOT-OD-16-012.
Application budgets may not exceed direct costs of $350,000 per year.
The total project period for an application submitted in response to this FOA may not exceed 4 years.