Investigators in the Pathogenesis of Infectious Diseases (PATH)

Funding Agency:
Burroughs Wellcome Fund

The Investigators in the Pathogenesis of Infectious Disease program provides opportunities for assistant professors to bring multidisciplinary approaches to the study of human infectious diseases. The goal of the program is to provide opportunities for accomplished investigators still early in their careers to study what happens at the points where the systems of humans and potentially infectious agents connect. The program supports research that sheds light on the fundamentals that affect the outcomes of these encounters: how colonization, infection, commensalism, and other relationships play out at levels ranging from molecular interactions to systemic ones.

PATH is a highly competitive award program that provides $500,000 over a period of five years to support accomplished investigators at the assistant professor level to study pathogenesis. The awards are intended to give recipients the freedom and flexibility to pursue new avenues of inquiry, stimulating higher risk research projects that hold potential for significantly advancing understanding of how infectious diseases work and how health is maintained.


  • Pre-proposal: July 14, 2017
  • Invited Application: November 15, 2017

Agency Website

Eligibility Requirements

The ideal candidate is an accomplished investigator at the mid-to late-assistant professor level with an established record of independent research in a tenure-track position or its well-supported equivalent in non tenure-offering departments.

Applications must be approved and signed by an official responsible for sponsored programs (generally from the grants office, office of research, or office of sponsored programs) at the degree-granting institution. Candidates will generally have a Ph.D. and/or a clinical doctorate (M.D., D.V.M., etc.).

  • Candidates must have an established record of independent research.
  • Citizens and non-citizen permanent residents of the U.S. and Canada are eligible.
  • Temporary residents of the U.S. and of Canada are eligible.
  • Citizens and non-citizen permanent and temporary residents of the U.S. and Canada who are legally qualified to work in the U.S. or Canada are eligible. Candidates who are temporary U.S. residents must hold a valid U.S. visa (J-1, H1B, F-1 or O-1 visas). Temporary Canadian residents must hold a valid Canadian visa (Study Permit, C-43, C44, C-10, or C-20 work permits/visas). n Candidates who will be promoted to Associate Professor by November 15, 2017 are not eligible to apply.
  • Candidates who have held or are currently holding a Burroughs Wellcome Fund award must contact BWF before writing the pre-proposal.



Funding Type


Duke Awardees

2002: Margarethe J. Kuehn, Ph.D.; Toxin trafficking via vesicles.
2011:  Jen-Tsan Ashley Chi, M.D., Ph.D.
Sequence determinant of the Plasmodium falciparum gene regulation by human microRNAs
2007: Raphael H. Valdivia, Ph.D.
Role of secreted bacterial proteases in chlamydial pathogenesis


African American
Junior Faculty
Native American


Environmental & Life Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

July 14, 2017