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Limited Competition: Competitive Revision Awards for the Clinical and Translational Science Award (CTSA) Program (U54 Clinical Trial Optional)
The purpose of this Funding Opportunity Announcement (FOA) is to solicit competitive revision (formerly known as competitive supplement) applications from awardees with active Clinical and Translational Science Award (CTSA) Program hub awards (UL1) to support the demonstration, and/or dissemination, and/or implementation of highly innovative and impactful translational science projects that address the goals of the CTSA Program and are beyond the original scope of the approved parent project Under this competitive revision, only applications for revisions to the UL1 award are allowed. Revisions to the linked KL2 and/or the TL1 awards are not allowed.
- Letter of Intent Due Date(s): 30 days prior to the application due date
- Application Due Date(s): September 25, 2019, September 25, 2020, September 27, 2021
PAR-19-337 Expiration Date September 28, 2021
Areas of Interest
Awardees funded through the following funding opportunity announcements are eligible to apply for one competitive revision per year through this funding opportunity announcement. Awardees funded through the expired FOA PAR-15-034 may apply through this funding opportunity announcement as well.
Clinical and Translational Science Award (U54) (PAR-18-464): https://grants.nih.gov/grants/guide/pa-files/PAR-18-464.html
Clinical and Translational Science Award (U54) (PAR-18-940): https://grants.nih.gov/grants/guide/pa-files/PAR-18-940.html
Under this competitive revision, only applications for revisions to the UL1 award are allowed. Revisions to the linked KL2 and/or the TL1 awards are not allowed.
To be eligible, the parent award (UL1) must be active (i.e. not be in an extension period), and the research proposed in the supplement must be accomplished within the remaining active project period for the existing UL1 parent award.
A CTSA Program hub is defined as a UL1 award with a linked KL2 award and an optional TL1 award. A hub that is in no-cost extension (NCE) status is not considered a currently funded CTSA Program hub (see https://ncats.nih.gov/ctsa/about/hubs). CTSA Program hub institutions include the recipients of the CTSA Program hub award, as well as any institutions listed as partners in the CTSA Program hub UL1 award.
Work must be accomplished within the remaining active project period for the existing UL1 parent award assuming a July start date for the revision. Projects with a total proposed duration of less than one year will not be accepted.
The PD/PI of the revision application must be the PD/PI of the parent UL1 award. Individual(s) must hold an active grant or cooperative agreement, and the research proposed in the supplement must be accomplished within the competitive segment of the active award. Individuals are encouraged to work with their organizations to develop applications for support.
The PDs/PIs of the parent grant may designate senior/key personnel to contribute to the scientific development or execution of the supplement project in a substantive, measurable way. Investigators who are not employed by and/or receive funding from a CTSA Program Institution may co-direct a project in partnership with a CTSA Program hub investigator using the multiple PD/PI option.
For supplements to parent awards that include multiple PDs/PIs, the supplement may be requested by any or all of the PDs/PIs (in accordance with the existing leadership plan) and submitted by the awardee institution of the parent award. The PD/PI, or contact PD/PI, in applications using the multiple PD/PI option, must be employed by a CTSA Institution. Investigators who are not employed by a CTSA Institution may co-direct a project in partnership with a CTSA investigator.
Do not use this competitive revision application to add, delete, or change the PDs/PIs listed on the parent award. Visit the Multiple Program Director/Principal Investigator Policy in the SF424 (R&R) Application Guide for more information.
Only one competitive revision application to a UL1 hub may be funded per year.
Application budgets are limited to no more than $750,000/year in direct costs excluding consortium/contractual F&A costs.
The UL1 parent award must be active when the application is submitted.
The project and budget periods must be within the currently approved project period for the existing parent UL1 award. Supplement award budgets and project periods will be based upon the time remaining in the parent award at the time the supplement award is made. See Section III.1 for additional information.
The requested project period may be from one to three years provided it is within the remaining project period of the current UL1 award.