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Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)
The purpose of this NOFO is to enhance the capability of NCATS CTSA Program KL2/K12 scholars and recipients of diversity and re-entry supplements (Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) (PA-23-189 and PA-21-071)) and Research Supplements to Promote Re-Entry, Re-integration into, and Re-training in Health-Related Research Careers (Admin Supp - Clinical Trial Not Allowed) (NOT-OD-23-170 and NOT-OD-21-134)) supported by the CTSA Program to conduct translational science research as they complete the transition to fully independent academic translational scientists.
These R03 grants will support different clinical and translational science research projects, including pilot and feasibility studies; secondary data analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. Research proposed in the R03 application may or may not include patient-oriented research. The R03 is, therefore, intended to support research projects that can be carried out in a short period of time with limited resources and that provide preliminary data to support submission of a subsequent R01, or equivalent, application.
- Letter of Intent Due Date(s): 30 days prior to the application due date
- Application Due Date(s): Feb. 20, 2024; June 18, 2024; Oct 17, 2024; Feb 17, 2025; June 17, 2025; Oct 17, 2025; Feb 18, 2026; June 17, 2026; Oct 19, 2026
PAR-21-121 Expiration Date October 20, 2026
Eligibility is limited to NCATS CTSA Program supported:
1) Scholars who received direct NCATS funding from the NCATS CTSA Program Institutional Career Development Core/Program (KL2/K12) and completed the KL2/K12 training program. Determination of eligibility will be based on the submitted and accepted KL2/K12 xTrain appointment forms. The expectation is that KL2/K12 scholars have completed the full mentored research career development program.
2) recipients of research supplements to promote diversity in health-related research supported by the CTSA Program (Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) (PA-23-189 and PA-21-071)) that are at the level of investigators developing independent research careers; or
3) recipients of research supplements to promote re-entry into biomedical and behavioral research careers supported by the CTSA Program (Research Supplements to Promote Re-Entry, Re-integration into, and Re-training in Health-Related Research Careers (Admin Supp - Clinical Trial Not Allowed) (NOT-OD-21-134 and NOT-OD-23-170)).
Applications with multiple PDs/PIs will not be accepted. Only single PD/PI applications are allowed. Only the PD/PI may be listed as a Senior/Key Person and provide a Biographical Sketch.
Scholars funded by KL2/K12 supplements supported by other NIH ICs are not eligible (e.g. RFA-DE-17-008, PA-18-920, NOT-AT-20-010, PA-18-426, PA-18-851, NOT-OD-20-022, NOT-OD-21-001, NOT-OD-22-192). The earliest award date for the R03 is one day after the completion of the scholar’s appointment or one day after the completion of the research supplement award. Applications must be submitted for R03 due dates within 2 years of completion of the KL2/K12 appointment or the research supplement. Eligibility for resubmissions will be extended for 12 months past the first submission. PD/PIs who have already successfully competed for a substantial NIH independent research award are ineligible. An investigator will retain their eligibility if they have already successfully competed for any of the smaller research awards, training, infrastructure, and career awards that are listed here, provided that each application is scientifically distinct.
Applicants are strongly encouraged to consult with NCATS about their proposal early in the planning of an application; questions regarding eligibility should be addressed prior to beginning to prepare the application by contacting the Scientific/Research contact listed in Section VII. Agency Contacts.
Application budgets are limited to direct costs up to $50,000 per year and need to reflect the actual needs of the proposed project.
The scope of the proposed project should determine the project period. The maximum period of support is 2 years.