LRRK2 Challenge

Funding Agency:
Michael J. Fox Foundation for Parkinson's Research

The Michael J. Fox Foundation for Parkinson’s Research (MJFF) seeks to support work that can significantly contribute to a better understanding of the gene/protein leucine-rich repeat kinase 2 (LRRK2), its relevance to Parkinson’s disease (PD) and effective ways to translate LRRK2 research into therapies for patients. Applicants may submit a proposal focused on a relevant area of LRRK2 for consideration of a one-year, $125,000 award. Successful applicants will be granted membership in the MJFF LRRK2 Consortium, where they can share information, data and resources with other awardees of this and other MJFF LRRK2-related efforts.

Deadline: Open

Agency Website

Areas of Interest

Priorities for 2014

The Foundation is focusing its efforts on:

  • Refining the regulatory path for cognitive impairment in Parkinson's disease
  • Validating the diagnostic criteria for mild cognitive impairment in Parkinson's disease.
  • Defining early changes and potential risk factors for Parkinson's disease cognitive decline and further progression to dementia
  • Understanding the underlying mechanisms that can inform targeted therapies, including the contribution of multiple pathologies

Eligibility Requirements

Applications may be submitted by:

  • U.S. and non-U.S. biotechnology/pharmaceutical companies or other for-profit entities, either publicly or privately held,
  • U.S. and non-U.S. entities, public and private non-profit entities, such as universities, colleges, hospitals, laboratories, units of state and local governments, and eligible agencies of the federal government.

Post-doctoral fellows are NOT eligible to apply as Principal Investigators to this program.

Amount

$125,000

Amount Description

MJFF intends to fund multiple proposals as part of this initiative. Invited applicants may request up to one year and $125,000 in total costs, inclusive of both direct and indirect costs. No more than 10% of the direct costs may go to indirect costs.

Funding Type

Grant

Eligibility

Faculty
Junior Faculty

Category

Medical - Basic Science
Medical - Clinical Science
Medical - Translational
Medical