LRRK2 Challenge

The Michael J. Fox Foundation for Parkinson’s Research (MJFF) seeks to support work that can significantly contribute to a better understanding of the gene/protein leucine-rich repeat kinase 2 (LRRK2), its relevance to Parkinson’s disease (PD) and effective ways to translate LRRK2 research into therapies for patients. Applicants may submit a proposal focused on a relevant area of LRRK2 for consideration of a one-year, $125,000 award. Successful applicants will be granted membership in the MJFF LRRK2 Consortium, where they can share information, data and resources with other awardees of this and other MJFF LRRK2-related efforts.

Deadline: Open
Areas of Interest
Priorities for 2014

The Foundation is focusing its efforts on:

  • Refining the regulatory path for cognitive impairment in Parkinson's disease
  • Validating the diagnostic criteria for mild cognitive impairment in Parkinson's disease.
  • Defining early changes and potential risk factors for Parkinson's disease cognitive decline and further progression to dementia
  • Understanding the underlying mechanisms that can inform targeted therapies, including the contribution of multiple pathologies
Eligibility Requirements

Applications may be submitted by:

  • U.S. and non-U.S. biotechnology/pharmaceutical companies or other for-profit entities, either publicly or privately held,
  • U.S. and non-U.S. entities, public and private non-profit entities, such as universities, colleges, hospitals, laboratories, units of state and local governments, and eligible agencies of the federal government.

Post-doctoral fellows are NOT eligible to apply as Principal Investigators to this program.

Amount Description
MJFF intends to fund multiple proposals as part of this initiative. Invited applicants may request up to one year and $125,000 in total costs, inclusive of both direct and indirect costs. No more than 10% of the direct costs may go to indirect costs.
Funding Type
Sponsor: Rolling