Sponsor Deadline
Posted: 4/12/2024

Medical Scientist Training Program (MSTP) (T32)

The goal of the Medical Scientist Training Program (MSTP) is to develop a diverse pool of well-trained clinician-scientist leaders available to address the nation’s biomedical research needs. Specifically, this funding announcement provides support to eligible, domestic organizations to develop and implement effective, evidence-informed approaches to dual-degree training and mentoring that will keep pace with the rapid evolution of the biomedical research enterprise and lead to the completion of both a clinical degree (for example, M.D., D.O., D.V.M., D.D.S., Pharm.D., etc.) and a research doctorate degree (Ph.D.).  

With the dual qualifications of a rigorous scientist and clinician, graduates will be equipped with the skills to develop research programs that accelerate the translation of research advances to the understanding, detection, treatment, and prevention of human disease, and to lead the advancement of biomedical research.  Areas of particular importance to NIGMS are optimizing training efficiency, fostering the persistence of alumni in research careers, and enhancing the diversity of the clinician-scientist workforce.  NIGMS expects that the proposed research training program will incorporate didactic, research, mentoring and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the nation.

This Notice of Funding Opportunity (NOFO) does not allow appointed Trainees to lead an independent clinical trial, but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.

NIGMS will accept only one MSTP application per institution. Interested applicants from within Duke should contact fundopps@duke.edu as early as possible.


  • T32 Due Dates: Jan. 25, May 25, Sep. 25

PAR-24-128 Expiration Date January 26, 2027


Eligibility Requirements

NIGMS allows multiple institutions to participate in a single MSTP application, where this may further advance the goals of the program.  A single contact institution would receive and administer the award.

The sponsoring institution must assure support for the proposed program. Appropriate institutional commitment to the program should be detailed in the Organizational Support Letter in the Letters of Support attachment. See the application instructions for the required Letters of Support instructions in Section IV.

As described in the instructions for the Training Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) in Section IV.2 below, NIGMS encourages multiple PDs/PIs, particularly when each brings a unique perspective and skill set that will enhance training. Note the following:

  • To provide research training leadership for the program, at least one of the training PDs/PIs should have a record of using rigorous and transparent methods in experimental design, data collection, analysis, and reporting in a biomedical research field applicable to the program.
  • Additional PDs/PIs may be included to strengthen the expertise of the PD/PI team. Examples include individuals such as program directors who regularly interact with students, or individuals with expertise in education, relevant social sciences, program evaluation, mentoring, or university administration. 

Any of the PDs/PIs may serve as the contact PD/PI. The contact PD/PI is expected to have a full-time appointment at the applicant organization unless extremely well-justified. If the full-time status of the contact PD/PI changes after the award, the organization must obtain prior program approval to appoint a new PD/PI or request a deviation from the full-time rule. The PD(s)/PI(s) will be responsible for:

  • The overall direction, management, administration, and evaluation of the program.
  • The day-to-day administration of the program, including direct involvement with trainees.
  • The selection and appointment of trainees to the research training program.
  • The selection of faculty mentors for the program, assessment of mentor performance, and ensuring the program deals appropriately with substandard mentor performance.
  • Monitoring and assessing the program and submitting all documents and reports as required.
  • Appointing members of the Advisory Committee (when applicable) and implementing their guidance as appropriate.