This Notice of Funding Opportunity (NOFO) invites applications to provide career development activities for a diverse pool of highly trained investigators in research areas of interest to the NHLBI. The career development will take place under the guidance of an experienced mentor in the biomedical, behavioral or clinical sciences leading to research independence. It is targeted toward individuals whose basic, clinical, and translational research interests are grounded in the advanced methods and experimental approaches needed to solve problems related to cardiovascular, pulmonary, and hematologic diseases and sleep disorders in the general and health disparities populations.
This NOFO is designed specifically to support candidates proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial. Applicants to this NOFO are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary study to an ongoing clinical trial to support the lead investigator should apply to the companion NOFO (RFA-HL-25-008).
Deadlines:
- Application Due Date(s): October 17, 2024; Feb 11, 2025; Oct 15, 2025; Feb 11, 2026; Oct 14, 2026; Feb 11, 2027
- AIDS Application Due Dates: Jan 7, 2025; May 7, 2025; Jan 7, 2026; May 7, 2026; Jan 7, 2027, May 7, 2027
RFA-HL-25-009 Expiration Date May 08, 2027
Any candidate with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director/Principal Investigator (PD/PI), is invited to work with his/her mentor and organization to develop an application for support. Multiple PDs/PIs are not allowed. Individuals from diverse backgrounds, including individuals from underrepresented racial and ethnic groups, individuals with disabilities, and women are always encouraged to apply for NIH support. See, Reminder: Notice of NIH's Encouragement of Applications Supporting Individuals from Underrepresented Ethnic and Racial Groups as well as Individuals with Disabilities, NOT-OD-22-019.
By the time of award, the individual must be a citizen or a non-citizen national of the United States or have been lawfully admitted for permanent residence (i.e., possess a currently valid Permanent Resident Card USCIS Form I-551, or other legal verification of such status).
Current and former PDs/PIs on NIH research project (R01), program project (P01), center grants (P50), Project Leads of program project (P01), or center grants (P50), other major individual career development awards (e.g., K01, K07, K08, K22, K23, K25, K76, K99/R00), or the equivalent are not eligible. Current and former PDs/PIs of an NIH Small Grant (R03), Exploratory/Developmental Grant (R21), Planning Grant (R34/U34), Dissertation Award (R36), or SBIR/STTR (R41, R42, R43, R44) remain eligible, as do PD/PIs of Transition Scholar (K38) awards and individuals appointed to institutional K programs (K12, KL2).
This funding opportunity may support individuals who propose to train in a new field or individuals who have had a hiatus in their research career because of illness or pressing family circumstances.
Eligible candidates must have research experience (length of time may vary) and be committed to developing into independent biomedical investigators in research areas relevant to the mission of the NHLBI (basic, clinical, or translational area realted to cardiovascular, pulmonary, or hematologic diseases and sleep disorders). The award will enable suitable faculty members holding doctoral degrees, such as the PhD, MD, DO, DVM in research or health professions, or an equivalent, to undertake special study and supervised research under a mentor who is an accomplished investigator in the research area proposed and has experience in developing independent investigators.
The program is not intended to support additional graduate training and is not intended to support career changes from non-research to research careers for individuals without prior research training.
Candidates must hold non-tenured faculty appointments (such as instructor, or assistant professor) before the award is made. The faculty appointment must not be contingent on receipt of the award.
Please note that a candidate’s race, ethnicity, or sex (including gender identity, sexual orientation, or transgender status) will not be considered as a factor in the application review process or when making funding decisions.
Current and former recipients of K12/KL2 support may apply for the K01 provided that they have no more than three years of K12/KL2 support by the time the K01 award is issued. The combined total of K12/KL2 plus K01 support must not exceed six years. A candidate for the K01 may not concurrently apply for or have an award pending for any other NIH career development award.