The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications that will advance mechanistic and translational research on the onset and worsening of mood and psychotic disorders during the menopausal transition (or perimenopause). In particular, NIMH seeks research that will advance understanding of the underlying neurobiological and behavioral mechanisms of mood disruption, emotion dysregulation, and psychosis during the menopausal transition and that will identify novel targets for future mental health interventions or prevention efforts
This NOFO uses the R01 grant mechanism, while the companion NOFO PAR-25-282 uses the R21 mechanism. Investigators proposing high risk/high reward projects, projects that lack preliminary data, or studies that utilize existing data may wish to apply using the R21 mechanism, while applicants with preliminary data who seek longer-term funding may wish to apply using the R01 mechanism.
Deadlines:
- R01 Due Dates: Feb 5, Jun 5, Oct 5
- R21 Due Dates: Feb 16, Jun 16, Oct 16
PAR-25-281 Expiration Date January 08, 2028
This NOFO encourages applications that incorporate teams with varied scientific backgrounds. Teams may include but are not limited to members from the fields of neuroscience, engineering, endocrinology, epidemiology, reproductive medicine, gerontology, gynecology, pharmacology, psychiatry, and psychology with the expertise necessary to conduct rigorous research. Teams led by or including those with lived experience with perimenopausal depression or psychosis are highly encouraged.