The Duke Funding Alert newsletter, published every Monday, provides information on all new and updated grants and fellowships added to the database during the prior week. This listserv is restricted to members of the Duke community.
National Center for Advancing Translational Sciences (NCATS) -- Collaborative Proposals
NCATS is now accepting proposals on a rolling basis to collaborate with Bridging Interventional Development Gaps (BrIDGs) and Therapeutics for Rare and Neglected Diseases (TRND) program scientists.
BrIDGs program scientists collaborate with researchers to advance candidate therapeutics for both common and rare diseases into clinical testing. Selected researchers partner with NCATS experts to generate pre-clinical data and clinical-grade material through government contracts to use in Investigational New Drug (IND) applications to regulatory agencies, such as the Food and Drug Administration. Investigators do not receive grant funds through this program. In general, BrIDGs staff provide synthesis, formulation, pharmacokinetic and toxicology expertise and resources to its collaborators.
The goal of the TRND program is to encourage and speed the development of new treatments for rare conditions and neglected tropical infectious diseases with high unmet medical needs. TRND program scientists and their collaborators move new therapeutic candidates through pre-clinical testing, from lead optimization to submission of an IND application. On a case-by-case basis, TRND supports clinical testing to demonstrate safety and proof-of-concept of investigational drug effectiveness in patients. These efforts effectively “de-risk” therapeutic candidates and make them more attractive for adoption by outside partners.