NIH Blueprint for Neuroscience Research: Tools and Technologies to Explore Nervous System Biomolecular Condensates (R21 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

The NIH Blueprint for Neuroscience Research is a collaborative framework through which 12 NIH Institutes, Centers and Offices jointly support neuroscience related research, with the aim of accelerating discoveries and reducing the burden of nervous system disorders (for further information, see The purpose of this Notice of Funding Opportunity (NOFO) is to support the development of innovative tools and/or technologies to monitor or manipulate biomolecular condensates (BMCs) in vivo and enable investigators to adopt these tools to answer outstanding questions in basic neuroscience. This research will transform our understanding of the mechanistic role of BMCs in human nervous system health and disease and may serve as the foundation for the development of novel BMC-based therapeutics.


  • Letter of Intent Due Date(s): October 14, 2023

  • Application Due Date:  November 14, 2023

RFA-DA-24-039 Expiration Date November 15, 2023

Agency Website



Amount Description

The combined budget for direct costs for the two year project period may not exceed $275,000. No more than $200,000 may be requested in any single year.

Funding Type





Engineering and Physical Sciences
Environmental & Life Sciences
Medical - Basic Science

External Deadline

November 14, 2023