NIH Director's Early Independence Award (DP5 - Clinical Trial Optional)

Funding Agency:
National Institutes of Health

The NIH Director's Early Independence Award supports exceptional investigators who wish to pursue independent research essentially directly after completion of their terminal doctoral/research degree or end of post-graduate clinical training, thereby forgoing the traditional post-doctoral training period and accelerating their entry into an independent research career. Applications are welcome from individuals of diverse backgrounds and perspectives and in any topic of relevance to the broad mission of NIH. The NIH Director's Early Independence Award is a component of the High-Risk, High-Reward Research program of the NIH Common Fund.

An applicant organization may submit up to two applications in response to this FOA.   

Deadlines:

  • Duke Internal Deadline: June 4, 2018 extended to August 1, 2018
  • Letter of Intent (optional): August 27, 2018
  • Application Due Date: September 27, 2018
  • AIDS Application Due Date: September 27, 2018

RFA-RM-18-010 Expiration Date September 28, 2018

Agency Website

Eligibility Requirements

Only single PD/PI applications are allowed. Applications with multiple PDs/PIs will not be accepted. Only the PD/PI may be listed as a Senior/Key Person and provide a Biographical Sketch.

There is no citizenship requirement for PDs/PIs. For applications submitted on behalf of non-U.S. citizens with temporary U.S. visas, visa status must allow the PD/PI to conduct the proposed research at the applicant institution. The applicant institution is responsible for determining and documenting that PD's/PI's visa will allow the PD/PI to remain in the U.S. for the duration of the award.

Time window for eligibility: Given the focus on early research independence, the receipt date of the terminal doctoral degree or end of post-graduate clinical training of the PD/PI must be between June 1, 2017 and September 30, 2019. The degree receipt date is that which appears on the official transcript for the degree. The end of post-graduate clinical training includes residency and fellowship periods. At the time of application, the PD/PI must not have served as a post-doctoral fellow following a previous (not the most recent) doctoral degree for more than twelve months.

At the time of award, either 1) the Early Independence investigator must have received a PhD, MD, DO, DC, DDS, DVM, OD, DPM, ScD, EngD, Dr PH, DNSc, ND (Doctor of Naturopathy), PharmD, DSW, PsyD, or equivalent doctoral degree from an accredited domestic or foreign institution (it is the responsibility of the sponsoring institution to determine if a foreign doctoral degree is equivalent), or 2) an authorized official of the degree-granting or training institution must certify that all degree requirements have been met and that the receipt date of the degree (as will appear on the transcript) will be before September 30, 2019; in addition, an authorized official of the host institution must certify that the PD/PI will be eligible to conduct independent research at the institution at the time of the project start date.

Level of effort: Individuals must commit at least 9.6 person-months each year (i.e., 80% effort of a 12-month appointment) during the first two years of the project period to research supported by the Early Independence Award. In the final three years of the project period, awardees may reduce effort toward the Early Independence Award project, but the total effort towards independent research in general must remain at least 9.6 person-months each year (i.e., 80% effort of a 12-month appointment).

Research independence at time of application: Individuals are eligible only if they, at the time of application submission, do not have research independence. Lack of research independence is defined functionally rather than by position title. Eligible individuals must have all the following characteristics:
 

  • The PD/PI's current research agenda is set through concurrence with mentors.
  • The PD/PI's research is funded primarily through support to other investigators (mentored fellowships such as NIH F31 or F32 Fellowships or NSF Graduate Research Fellowships do not preclude eligibility).
  • The PD/PI does not have any space assigned directly by the institution for the conduct of his/her research.
  • The PD/PI, according to institutional policy, cannot apply for an NIH R01 grant without special waiver or exemption from the institution.

 
Though the PD/PI must not be functionally independent at the time of application submission, s/he may become functionally independent prior to time of award and still retain eligibility for the award.
 

Amount

$1,250,000

Amount Description

Awards will be for up to $250,000 in direct costs per year, plus applicable Facilities and Administrative (F&A) costs.
 
The project period is limited to five years.

Funding Type

Grant

Eligibility

Junior Faculty
Medical Fellow/Resident

Category

Engineering and Physical Sciences
Environmental & Life Sciences
Medical
Medical - Basic Science
Medical - Clinical Science
Medical - Translational
Social Sciences

Internal Nomination

Owing to the sponsor's restriction on the number of applications that may be submitted from Duke, anyone wishing to pursue nomination should submit the following materials as one PDF.

* A letter of support from dean/chair - 1 to 1.5 pages
* Project summary - 2 to 4 pages
* CV or NIH Biosketch - please enter month, day, and year of degrees and employment. Please include job titles.

Applicants will need to submit internal materials through My Research Proposal. https://www.grantinterface.com/Common/LogOn.aspx?eqs=ApVvmgXCk2Uj7AzWyDEJKQ2

Instructions for setting up your account and uploading internal applications can be found here: https://ors.duke.edu/sites/default/files/atoms/files/Applicant%20Instruc...

Internal Deadline

August 1, 2018

External Deadline

September 27, 2018