NIH Director's New Innovator Award Program (DP2 - Clinical Trial Optional)

Funding Agency:
National Institutes of Health

The NIH Director’s New Innovator Award Program supports early stage investigators of exceptional creativity who propose highly innovative research projects with the potential to produce a major impact on broad, important problems relevant to the mission of NIH. For the program to support the best possible researchers and research, applications are sought which reflect the full diversity of the research workforce. Individuals from diverse backgrounds and from the full spectrum of eligible institutions in all geographic locations are strongly encouraged to apply to this Funding Opportunity Announcement. In addition, applications in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, topics in the behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. The NIH Director's New Innovator Award Program complements ongoing efforts by NIH and its Institutes and Centers to fund early stage investigators through R01 grants, which continue to be the major sources of NIH support for early stage investigators. The NIH Director’s New Innovator Award Program is a component of the High-Risk, High-Reward Research Program of the NIH Common Fund.

Deadlines:

  • Application Due Date(s): August 26, 2019
  • AIDS Application Due Date(s):  August 26, 2019

RFA-RM-19-006 Expiration Date: August 27, 2019

Agency Website

Eligibility Requirements

Applicants must meet the definition of an Early Stage Investigator (ESI) at the time of application. An ESI is a new investigator (defined as a PD/PI who has not competed successfully for a significant NIH independent research award) who is within 10 years of completing his/her terminal research degree or end of post-graduate clinical training. See the Office of Extramural Research for a complete list of NIH grants that do not disqualify a PD/PI as a new investigator and for frequently asked questions about the NIH Early Stage Investigator (ESI) Policy.
 
An extension to the 10-year period may be granted under special circumstances (e.g., family care responsibilities, extended periods of clinical training, disability or illness, etc.). To request an extension, an applicant MUST complete the “Form for Requesting an Extension in the Early Stage Investigator (ESI) Period.” It may take several weeks for the review process for the request, so applicants should plan accordingly. Note: If an applicant is not identified as an ESI in the eRA Commons, it may result in the application not being reviewed. Applicants are responsible for reviewing and/or updating their degree information in their eRA Commons account in a timely fashion.
 
Applicants must hold an independent research position at a domestic (U.S.) institution by September 1, 2019. For this FOA, an “independent research position” is a position that automatically confers eligibility to the investigator (based on institutional policy) to apply for R01 grants with appropriate institutional commitment of facilities for the conduct of the proposed research. Investigators still in training or mentored status (postdoctoral fellows) are not eligible to apply unless they have a written commitment from the institution stating they will be in an independent faculty position by September 1, 2019. The commitment is certified by the institution's submission of the application.
 
Applicants may submit or have an NIH R01 or other equivalent grant application pending concurrently with their NIH Director’s New Innovator Award application if it does not overlap substantially with their New Innovator Award application. However, if that pending grant becomes active prior to the NIH Director’s New Innovator Award, the applicant is no longer eligible to receive the New Innovator Award.
 
Awardees are required to commit at least three person-months (25%) of their research effort each year to activities supported by the New Innovator Award.
 
For more details regarding eligibility requirements, see FAQs on the New Innovator website.

Applicant organizations may submit more than one application, provided that each application is scientifically distinct. Only one application per PD/PI is permitted in response to this FOA.

Amount

$1,500,000

Amount Description

Awards are multi-year funded with all funds disbursed in the first year of the award. Awards will be up to $1,500,000 in direct costs (the equivalent of $300,000 in Direct Costs each year for five years) plus applicable Facilities and Administrative (F&A) costs to be determined at the time of award.

Funding Type

Award
Grant

Duke Awardees

2011
Nicolas Buchler, PhD
Departments of Biology and Physics
Project Title: Rewiring The Yeast Brain: Redundancy And Interference In Genetic Networks

Charles Gersbach, PhD
Pratt School of Engineering
Project Title: Engineering Morphogenetic Factors For Enhanced Genetic Reprogramming

David Tobin, PhD
Molecular Genetics and Microbiology
Project Title: Modulating Eicosanoids To Treat Tuberculosis: Personalized, Host-Directed Therapy

Seok-Yong Lee, PhD
Department of Biochemistry
Project Title: Pharmacology and Biophysics of the Voltage-Gated Sodium Channel Nav 1.7

2009
Michel Bagnat
Duke University School of Medicine
Discovering New Regulators of CFTR and Fluid Secretion in Zebrafish

2008
Chay T Kuo, PHd
Discovering Pathways Regulating Neurogenesis and Brain Remodeling After Injury

Eligibility

Junior Faculty
Post Doctoral Fellows

Category

Engineering and Physical Sciences
Environmental & Life Sciences
Medical
Medical - Basic Science
Medical - Clinical Science
Medical - Translational
Social Sciences

External Deadline

August 26, 2019