Sponsor Deadline
Posted: 3/25/2024

NIH Director's Pioneer Award (DP1 - Clinical Trial Optional)

The NIH Director’s Pioneer Award Program supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator’s research program or elsewhere. To support innovative and novel research across the vast NIH mission, individuals from diverse backgrounds (including those from underrepresented groups; see Notice of NIH’s Interest in Diversity) and from the full spectrum of eligible institutions in all geographic locations are encouraged to apply. Applications in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, topics in the behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. The NIH Director’s Pioneer Award is a component of the High-Risk, High-Reward Research (HRHR) Program of the NIH Common Fund.


  • Application Due Date(s): September 9, 2024
  • AIDS Application Due Date: September 9, 2024

RFA-RM-24-002 Expiration Date: September 10, 2024

Eligibility Requirements

Applicant organizations may submit more than one application, provided that each application is scientifically distinct. Individuals may submit only one application as a PD/PI in response to this NOFO.

Only single PD/PI applications are allowed. Applications with multiple PD(s)/PI(s) will not be accepted.

Amount Description

Awards will be for $700,000 in direct costs per year, plus applicable Facilities and Administrative (F&A) costs.

The project period is limited to five years.