NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.

Companion FOAs:

PA-20-194, Parent R21 Exploratory/Developmental Grant, Clinical Trial Required

PA-20-196, Parent R21 Exploratory/Developmental Grant, Basic Experimental Studies with Humans Required


  • R21 Deadlines: Feb. 16, Jun. 16, Oct. 16.
  • AIDS Deadlines: Jan. 7, May 7, Sep. 7.

PA-20-195 Expiration Date: New Date January 8, 2025 per issuance of NOT-OD-24-099. (Original Expiration Date: May 8, 2023)

Agency Website



Amount Description

The combined budget for direct costs for the two-year project period may not exceed $275,000. No more than $200,000 may be requested in any single year.

Funding Type



Junior Faculty


Engineering and Physical Sciences
Environmental & Life Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational
Social Sciences

External Deadline

June 16, 2024