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NIH Health Care Systems Research Collaboratory - Demonstration Projects for Pragmatic Clinical Trials (UG3/UH3)
The purpose of this FOA is to solicit applications to support Demonstration Projects that include an efficient, large-scale pragmatic clinical trial. Trials must be conducted across two or more health care systems (HCS) and must be conducted as part of the NIH HCS Research Collaboratory supported through the NIH Common Fund. (See https://commonfund.nih.gov/hcscollaboratory). Awards made through this FOA will initially support a one-year milestone-driven planning phase (UG3), with possible rapid transition to the second implementation phase (UH3) for a pragmatic trial Demonstration Project. UH3s will be awarded after administrative review of eligible UG3s that have met the scientific milestone and feasibility requirements necessary for the UH3 implementation phase, depending on the availability of funds. The UG3/UH3 application must be submitted as a single application, and applicants should note specific instructions for each phase in this FOA.
The overall goal of the NIH HCS Research Collaboratory program is to strengthen the national capacity to implement cost-effective, large-scale research studies that engage health care delivery organizations as research partners. The NIH HCS Research Collaboratory Program has established a Collaboratory Coordinating Center (CCC) that is providing national leadership and technical expertise in all aspects of research with HCS. After awards are made by NIH, the CCC (https://www.nihcollaboratory.org/Pages/default.aspx) and the NIH will work with successful awardees from this FOA to facilitate the planning and rapid execution of high impact Demonstration Projects that conduct research studies in partnerships with health care delivery systems, ultimately making available data, tools and resources from Collaboratory research projects to develop a broadened base of research partnerships with HCS.
- Letter of Intent Due Date: 30 days prior to the application due date
- Application Due Date(s): June 2, 2017
- AIDS Application Due Date(s): June 2, 2017
RFA-RM-16-019 Expiration Date June 3, 2017
The application budget for the one-year UG3 phase is limited to $500,000 in direct costs. Costs for each year of the UH3 phase are limited to $1 million in direct costs.
The maximum period of funding for the UG3 phase is one year and the maximum period of funding of the UH3 phase is four years, for a total of five years for the entire UG3/UH3 award.