Fogarty HIV Research Training Program for Low-and Middle-Income Country Institutions (D43 Clinical Trial Optional)

Funding Agency:
National Institutes of Health

The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications for research training programs to strengthen the scientific capacity of institutions in low- and middle-income countries (LMICs) to conduct HIV research relevant to the evolving HIV epidemic in their country.

This FOA can support training for conducting research in a broad range of HIV research areas across HIV prevention, treatment, care, and quality of life continuum. This includes basic, epidemiologic, clinical, behavioral and social sciences, community-based, implementation, operations, health services, and health systems research. Cross-disciplinary research as well as HIV associated comorbidities and coinfections affecting the HIV epidemic will be supported under this FOA.

An application should focus the proposed training program to strengthen research capacity in a defined HIV scientific area at a specific LMIC institution and collaborating LMIC partner institutions.

This FOA allows qualified Trainees to serve as the lead investigator of an independent clinical trial; or to propose a separate ancillary study to an existing trial under the mentorship of an appropriate clinical researcher or to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

The HIVRT Program encourages applications for three different Funding Opportunity Announcements (FOAs). This FOA (D43) encourages applications to support research training to strengthen scientific expertise needed for HIV research at LMIC institutions. The second FOA (D71) PAR-19-284 encourages planning grant applications from LMIC institutions to develop a training program and application to submit under this FOA at a later date. The third FOA (G11) encourages applications for infrastructure development training in several research infrastructure functions described in PAR-19-285.


  • Letter of Intent Due Date: July 20, 2019; July 20, 2020; July 20, 2021
  • AIDS Application Due Date(s): August 20, 2019; August 20, 2020; August 20, 2021

PAR-19-283 Expiration Date August 21, 2021

Agency Website

Eligibility Requirements

An application may be submitted by a foreign institution in an eligible low- or middle-income country (LMIC) or by a domestic (U.S.) institution that demonstrates collaboration with an LMIC institution in eligible low- or middle-income country(ies). Collaboration should be documented by joint publications, grants or previous research training activities.

LMICs are defined by the World Bank classification system according to Gross National Income (GNI) per capita as “low-income,” “lower-middle-income,” and “upper-middle-income” ( ). See Country Eligibility for Fogarty International Training Grants ( ) for additional restrictions. Other High-Income Country (HIC) or ineligible LMIC Faculty and institutions may be named as partners and serve as training sites.

The applicant institution must assure support for the proposed program. Appropriate institutional commitment to the program includes the provision of adequate staff, facilities, and educational resources that can contribute to the planned program.

The applicant institution must have a strong and high-quality research program in the area(s) proposed under this FOA and must have the requisite faculty, staff, potential trainees and facilities on site to conduct the proposed institutional program. In many cases, it is anticipated that the proposed program will complement other ongoing career development programs occurring at the applicant institution and that a substantial number of program faculty will have active research projects in which participating trainees may gain relevant experiences consistent with their research interests and goals.

The PD/PI should be an established investigator in the scientific area in which the application is targeted and capable of providing both administrative and scientific leadership to the development and implementation of the proposed program.

PD(s)/PI(s) on applications from U.S. institutions are expected to demonstrate a history of relevant HIV research collaboration with researchers or faculty at the LMIC institution named in the application. Similarly, PD(s)/PI(s) on applications from LMIC institutions are expected to demonstrate a history of relevant HIV research collaboration with researchers or faculty at the U.S. institution or collaborating LMIC institutions named in the application.

The PD/PI will be responsible for the selection and appointment of trainees to the approved research training program, and for the overall direction, management, administration, and evaluation of the program.

The PD/PI will be expected to monitor and assess the program and submit all documents and reports as required.

The PD/PI is responsible for appointing members of the Training Advisory Committee (TAC) and for establishing a structure to obtain regular feedback from the TAC.

U.S. and LMIC applicants who meet the eligibility requirement are encouraged to apply as a Multiple PD/PI with either serving as the contact PI (see ( for more information).



          Amount Description

          Application budgets are limited to $280,000 direct costs per year exclusive of consortium indirect costs.

          The maximum project period is 5 years.

          Funding Type





          Curriculum Development
          International Opportunities
          Medical - Basic Science
          Medical - Clinical Science
          Social Sciences

          External Deadline

          August 20, 2019