Notice of Special Interest: Administrative Supplements to Participate in the NCI Early-stage Surgeon Scientist Program (ESSP)

Funding Agency:
National Institutes of Health

Applications to support extramural candidates must be submitted using the following opportunity or its subsequent reissued equivalent:

PA-20-272 - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional).

All instructions in theSF424 (R&R) Application Guide and the funding opportunity announcement used for submission must be followed, with the following additions:

Eligibility and Eligible Institutions:

Active NCI P30 Cancer Center or CPACHE U54 Center ISUPS awardees are eligible to apply. Future years may be contingent upon successful renewal of the parent award.

Not Eligible:

Centers which will enter an extension year during the fiscal year in which this award will be made are not eligible to apply for the supplement since new administrative supplements cannot be paid to grants in an extension year. Contact the NCI program director if a renewal application is pending to determine eligibility.

Eligibility and Eligible Individuals (ESSP-Participant Candidate):

ESSP-Participant Candidate Requirements:

  • Must be a U.S.-licensed surgeon scientist with active surgical duties at an NCI-designated Cancer Center (P30) or an ISUPS funded by a CPACHE U54 or be a Physician Early Investigator at NCI.
  • Must be within the first 1-3 years of tenure-track academic appointment and must conduct research on cancer-related basic or translational science.
  • Must commit a minimum of 6 person-months (50% full-time professional effort) to the ESSP award.
  • Current and/or former PDs/PIs on any NIH awards are not eligible candidates, with the following exceptions:
    • PD/PIs of NIH Fellowships, PD/PIs of Loan Repayment Program (LRP) awards, and individuals appointed to institutional T programs (T32). These individuals remain eligible candidates.


The candidate must be nominated by the Center Director (Principal Investigator (PI) of the P30 CCSG or PI of the U54 CPACHE) based on the candidate’s qualifications, interests, accomplishments, motivation and plans to pursue a career as a surgeon scientist with a focus on cancer-related research.

Number of Applications:

  • Only one submission per year per NCI-designated Cancer Center made through the PI of the P30 is permitted (consortium centers may submit only one application) and one submission per year per CPACHE program made through the PI of the U54 is permitted. The CPACHE U54 PI may only nominate one candidate from one of the CPACHE institutions serving underserved health disparity populations and underrepresented students (ISUPSs). The NCI-designated Cancer Center must apply for a P30 supplement; the CPACHE ISUPS must apply for a U54 supplement.
  • Only one submission per intramural NCI Branch will be considered each year.

Applications must be submitted by the Application Due Dates of December 8, 2021, December 8, 2022, and December 8, 2023, until 5:00 PM local time of applicant organization, for possible funding in FY2022, FY2023, and FY2024, respectively.





Medical - Basic Science
Medical - Clinical Science
Medical - Translational

Internal Nomination

If you are interested in applying for this opportunity, please send the following in one PDF to Dena Buchanan at by Monday, October 3rd, 2022.

  • 2 page description of the project including the following:

    • Title of proposal
    • Brief statement of candidate’s eligibility
    • Brief description of the proposal including the candidate’s career goals and objectives, and coursework and professional development plan
  • Draft budget and budget justification
  • NIH biosketches for candidate, mentor and co-mentors (in the updated NIH format)

All applicants will be notified no later than October 14th, 2022.


Internal Deadline

October 3, 2022

External Deadline

December 8, 2022