The purpose of this Notice is to inform potential applicants of the NIAAA’s special interest in research project applications studying the harmful effects of alcohol on the body’s tissues, organs, and systems in diverse populations across the lifespan.

Applications submitted to this NOSI are expected to elucidate the complex biology of alcohol-induced pathology and address any areas where knowledge gaps exist. Research on understanding and managing AROD is still needed. To address these needs, research approaches must be conducted ranging from the fundamental mechanisms to clinical studies that analyze existing, or newly collected, data and biological specimens using novel analytical tools. Basic research programs that integrate host and environmental factors with clinical aspects and identify mechanisms or processes related to clinically relevant pathological conditions, and/or translational studies that are potentially interventional and that identify therapeutic targets for the treatment of AROD are of particular interest.

This notice applies to due dates on or after February 5, 2021 and subsequent receipt dates through May 8, 2023.  

NOT-AA-20-024