Sponsor Deadline
Posted: 4/11/2024

Notice of Special Interest (NOSI): Administrative Supplements for NCI Global Oncology Mentored Research

Through this Notice of Special Interest (NOSI), the National Cancer Institute (NCI) encourages eligible grantees to apply for administrative supplements to support cancer research career development of early-stage Low- and Middle-Income Country (LMIC) investigators (ESLIs). The NCI Global Oncology Mentored Research Supplement initiative is designed to support high-quality mentored research experiences for ESLIs within the context of NCI extramural research projects. The overarching goal of this supplement is to strengthen the capacity of LMIC investigators to conduct high-quality independent and/or collaborative research in their home institutions thereby generating context-appropriate evidence to address the growing cancer problem in LMICs.

Cancer poses an increasing health and economic burden globally, but the impact is especially profound in LMICs where as many as 70% of all cancer deaths occur. Globally, cancer incidence and mortality are predicted to continue to increase over the next several decades, accelerating most rapidly in LMICs where capacity for cancer control is limited.There is an urgent need to ramp up cancer research in LMICs to generate LMIC-specific data/evidence to inform cancer prevention and control efforts locally. LMIC investigators are well positioned to lead innovative and impactful research in LMICs as they best understand the local cultures, as well as the unique needs, challenges, and opportunities. As global research collaborations are becoming increasingly critical to answer the complex cancer research questions in LMICs, concerted and deliberate efforts are needed to strengthen the research capacity of LMIC investigators to maximize research impact and foster equity in global research collaborations.

Deadline: May 15, 2024


Eligibility Requirements

Eligible Parent Awards and Number of Applications

For the purpose of this NOSI, eligible activity codes for applications are limited to the following: R01, R35, R37, P01, P20, P50, U01, U19, U54, UH2, UH3, UG1, UG3 or UM1. No other grant or cooperative agreement mechanisms are eligible for this program.

Note: Adding a foreign component under a grant or cooperative agreement to a domestic or foreign organization requires NCI prior approval.

A parent award may support more than one ESLI on a supplement; however, each request must be strongly justified and include assurances that each candidate will have a scientifically distinct research project and will receive appropriate mentoring. NCI staff will consider the nature of the parent grant, the circumstances of the request, and the program balance.

ESLI candidates may receive support from only one administrative supplement at a time, but may be supported by more than one supplement during the development of their research careers. Priority will be given to ESLIs who have not previously been supported under this mechanism. Support under the supplement is not transferable to another individual or transportable to another institution.

Program Director/Principal Investigator (PD/PI)

PD/PI must hold an active eligible grant or cooperative agreement supported through NCI, and the research proposed in the supplement must be accomplished within the competitive segment of the active award. The PI of the parent grant is ultimately responsible for the supplement

For supplements to parent awards that include multiple PDs/PIs, the supplement may be requested by any or all of the PDs/PIs (in accordance with the existing leadership plan) and submitted by the recipient institution of the parent award.

In addition, sub-project directors on multi-component research grants (e.g., P01, P50, U54) may request supplements to their project through the overall PD/PI of the grant.