This Notice of Special Interest (NOSI) encourages the translation of the novel neurotechnologies, funded through the Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative and overseen by the NIH Blueprint MedTech program. Academic and Small Business Concerns (SBCs) are encouraged to submit grant applications that propose non-clinical validation for subsequent clinical feasibility studies. Applications supporting the development and translation of groundbreaking neurotechnologies that fit within the mission of the BRAIN Initiative are encouraged.
This NOSI is intended to alert applicants that there is a need to help transition BRAIN Initiative-relevant technologies from early device development to first-in-human studies. Projects that fit the following categories can be submitted through the Blueprint MedTech Program.
BRAIN will support the following efforts coming into the BP MedTech UG3/UH3 and U44 funding opportunities:
- Projects developing novel invasive neurostimulation devices for the human central nervous system (CNS).
- Projects developing novel invasive brain recording devices for the human CNS.
- Projects developing novel non-invasive brain stimulation devices for the human CNS. These devices should aim to achieve brain stimulation resolution of sub-millimeter at the cortical surface and depth. These approaches may incorporate electromagnetic, mechanical, or combination biological and device means (e.g., optogenetics).
This notice applies to due dates on or after February 18, 2022, and subsequent receipt dates through June 20, 2024.
Deadlines: Feb 18, 2022; Jun 20, 2022; Oct 18, 2022; Feb 21, 2023; Jun 19, 2023; Oct 18, 2023; Feb 20, 2024; Jun 20, 2024
NOT-NS-22-052