Sponsor Deadline
Posted: 2/21/2025

Notice of Special Interest (NOSI): Firearm Injury and Mortality Prevention Research

The purpose of this Notice is to highlight interest in research to improve understanding of the determinants of firearm injury, the identification of those at risk of firearm injury (including self- and other-directed, victims and perpetrators, accidental injury), the development, piloting, and testing of innovative interventions to prevent firearm injury and mortality, and the examination of approaches to improve the implementation of existing, evidence-based interventions to prevent firearm injury and mortality.

Research encouraged by this NOSI is consistent with a broad public health approach to firearm injury and mortality prevention including:

  1. identifying those at risk for firearm injury and mortality (self- and other-directed; victims and perpetrators; accidental injury)
  2. development, piloting, and/or testing of theoretically-grounded programs to prevent firearm injury and mortality
  3. implementation research to explore the barriers and facilitators to support broader adoption of effective programs.

In addition to interventions delivered by healthcare providers and systems, this NOSI encourages research delivered in community settings, and that integrates individual, family, interpersonal, community, and structural or system (e.g., criminal or juvenile justice, child welfare, drug courts) approaches to firearm injury and mortality prevention. Thus, development of cross-sector partnerships and/or integration across disparate databases may be necessary.

This NOSI is comprehensive in its consideration of risk for victimization and/or perpetration across the lifespan and across sexual and gender identities, people with developmental disabilities or cognitive impairments (e.g., Alzheimer’s disease and its related dementias), comorbid conditions (e.g., psychiatric or substance use disorders), or other at-risk populations such as pregnant and post-partum individuals, justice/legal system involved individuals, veterans, and members of the military. In addition, consideration of NIH designated health disparity populations (who are often disproportionately impacted by firearm injury and mortality), is encouraged: specifically, Blacks/African Americans, Hispanics/Latinos, American Indians/Alaska Natives, Asian Americans, Native Hawaiians and other Pacific Islanders, socioeconomically disadvantaged populations, underserved rural populations, and sexual and gender minorities. Please refer to specific bullets below to obtain information about priority populations for each participating institute, center, or office.

This notice applies to due dates on or after February 5th, 2023 and subsequent receipt dates through February 5th, 2026.

NOT-OD-23-039