Notice of Special Interest (NOSI) in NINDS mission relevant Pain Research

Funding Agency:
National Institutes of Health

The purpose of this Notice of Special Interest (NOSI) is to outline NINDS priorities for applications in the field of pain research in Fiscal Year 2022. Recognizing the urgent need to understand the basic science aspect of pathological pain to improve its management, Fiscal Year 2022 draft budgets from the President, House, and Senate each include proposals to increase funding for pain research within NINDS’ mission. With this NOSI, NINDS wishes to inform the science community of the pain research opportunities that will present themselves, if funds become available. To be considered for funding through this initiative in Fiscal Year 2022, applications will need to be submitted to corresponding due dates starting in January or February 2022 so they can undergo Scientific Merit and NINDS Advisory Council review for the September 2022 Council round.

For funding consideration, applicants must include “NOT-NS-22-050” (without quotation marks) in the Agency Routing Identifier field (box 4B) of the SF424 R&R form. Applications without this information in box 4B will not be considered for this initiative. Applications deemed nonresponsive to the terms of this notice will not be considered for this initiative.

Although there is still some uncertainty about the final availability of funds, we are excited by the potential to accelerate discovery and therapy development in this critical area, and we hope to encourage investigators to consider submitting applications that can advance our knowledge of the nature of pain and its treatment. Specific areas of scientific need identified by NINDS are described below.

Pain is a critical national health problem. New and innovative advances are needed in nearly every area of pain research. This NOSI is specific for pain conditions within NINDS’ mission, which includes but is not limited to cellular and molecular pain research, neuropathic pain not associated with cancer treatments or diabetes, pain due to damage to nerves or other parts of the nervous system, and pain associated with neurological disorders such as Parkinson’s disease. Please reach out to the research contacts listed in the NOSI to confirm the NINDS mission relevance of your project prior to submission.

The following topic areas are not intended to be comprehensive or exhaustive. Synergistic studies that reach across two or more of these areas are encouraged. Interdisciplinary and multidisciplinary research is especially encouraged, as is research that involves specific cooperation between basic, translational, and clinical scientists.

This notice applies to due dates on or after January 25, 2022 and subsequent receipt dates through May 8, 2022. 





Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

May 7, 2022