This initiative will solicit applications that propose the development and early stage validation of novel small animal models and/or human cellular microphysiological systems of HIV infection that better recapitulate the complex interactions that occur between cells of the CNS and the immune system in people with HIV (PWH). The goal of this initiative is to promote a significant improvement in the translational relevance of NeuroHIV models, specifically in the context of chronic HIV infection of the CNS in the modern antiretroviral therapy (ART) era under conditions of viral suppression.
Deadlines:
- Letter of Intent Due Date(s): November 01, 2024
- AIDS Application Due Date: December 02, 2024
RFA-NS-24-035 Expiration Date December 03, 2024
Application budgets are limited to $600,000 in direct costs/year and need to reflect the actual needs of the proposed project.
The total project period for a combined R61/R33 application submitted in response to this NOFO may not exceed four years, with no more than two years for the R61 phase and no more than three years for the R33 phase.