Ocular Surface Innervation from Cell Types to Circuit Functions (U01 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) aims to identify and support collaborative projects that will comprehensively delineate ocular surface innervation – from corneal sensation to pain circuits and tearing reflexes. The Request for Applications (RFA) aims to explore this system at three levels of analysis: morphologic, molecular, and functional. Successful projects will incorporate and integrate at least two of these levels of analysis, and ideally all three. Collaborative multi-disciplinary teams are expected with investigators having complementary areas of expertise. The premise of this FOA is that such basic biology will facilitate a deeper understanding of related pathobiology including neuropathic ocular pain and dry eye disease that will lay a foundation for future translational and clinical research on the anterior segment of the eye. 


  • Letter of Intent: Feb. 7, 2022
  • Application: March 7, 2022

RFA-EY-21-004 Expiration Date March 8, 2022





Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

March 7, 2022