The OpenScope program is soliciting proposals for experiments to be carried out using the “Allen Brain Observatory” in vivo imaging and electrophysiology platforms in the brains of mice. Data will be collected by skilled operators at the Allen Institute and will be packaged in a standardized format and distributed to external teams for their own analysis. In the current call for proposals, recordings will be targeted to the visual pathways of mice passively viewing a stimulus monitor (future calls for proposals may include more brain regions and/or active behavioral tasks). We anticipate selecting three projects in 2021 distributed across Allen Brain Observatory rigs: Neuropixels electrophysiology and two-photon imaging. The resulting cellular data (spiking activity and segmented ROI) and meta-data will be delivered to the applicant team for their own subsequent analysis and publication. Experiments should be designed to address fundamental questions related to the function of the mammalian neocortex and associated structures in health or disease.
Required Letter of Intent Due: September 22nd, 2021 (5 pm Pacific)
Full Proposal Due: November 22nd, 2021 (5 pm Pacific)