Partnering Research and Community Organizations for Novel Health Equity Research: Addressing Social and Clinical Determinants of Maternal Health

Funding Agency:
Patient-Centered Outcomes Research Institute

Significant disparities in maternal mortality and severe maternal morbidity persist among Black or African-American people, American Indian/Alaska Native people, Hispanic people, people with disabilities, residents of rural areas, and people of lower socioeconomic status. Because social determinants of health are recognized as important drivers of disparities in health outcomes, addressing these disparities requires evidence-based solutions that comprehensively address both the clinical and social needs of communities impacted by these disparities.

The Partnering Research and Community Organizations for Novel Health Equity Research: Addressing Social and Clinical Determinants of Maternal Health Targeted PCORI Funding Announcement (Partner Targeted PFA) seeks to fund high-quality, comparative clinical effectiveness research (CER) studies that focus on multicomponent, multilevel interventions simultaneously addressing health conditions and social determinants of health to improve maternal health outcomes.

The Partner Targeted PFA, which supports PCORI’s National Priorities for Health, including Achieve Health Equity, intends to fund CER studies in which community organizations are full partners in the work, are in leadership roles, and are partners in critical decision making alongside research organizations. While the funding announcement will be released in January 2023, this preannouncement is provided to allow potential applicants additional time to identify collaborators, obtain stakeholder input on potential CER studies, and develop responsive, high-quality proposals.

LOI Deadline: Feb. 7, 2023

Agency Website

Areas of Interest

PCORI seeks to fund rigorous high-quality studies that address the following research question: What is the comparative effectiveness of multicomponent, multilevel interventions to improve maternal outcomes for individuals from populations highly impacted by maternal health disparities? Proposed CER studies may focus on pre-and/or postnatal care and should include at least one of each of the following types of interventions:

  • Health systems strategies to address disparities in maternal health outcomes (e.g., data accountability measures; bias awareness training; trauma-informed care; team-based care; community-informed models of care; telehealth; standardized protocols for monitoring/treatment of hypertension, substance use, depression, and diabetes)
  • Strategies to address social determinants of health (e.g., active assistance with resources; medically tailored meals; vouchers for food, housing, or other needs; medical-legal partnerships; integrated social services in clinical settings)

Funding Type





Community Outreach and Engagement
Medical - Clinical Science
Medical - Translational
Social Sciences

External Deadline

February 7, 2023