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Paul Calabresi Career Development Award for Clinical Oncology (K12 Clinical Trial Optional)
The purpose of the Paul Calabresi Career Development Award for Clinical Oncology (PCACO) is to increase the number of clinician-scientists trained in clinical and translational cancer research, and to promote their career development as cancer researchers.
This Funding Opportunity Announcement (FOA) allows appointment of Scholars proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary study to an existing trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development.
Application Due Date(s): June 15, 2022; June 15, 2023, June 17, 2024
PAR-22-136 Expiration/Closing Date: June 18, 2024
The sponsoring institution must assure support for the proposed program. Appropriate institutional commitment to the program includes the provision of adequate staff, facilities, and educational resources that can contribute to the planned program.
The applicant institution must have a strong and high-quality research program in the area(s) proposed under this FOA and must have the requisite faculty, staff, potential trainees and facilities on site to conduct the proposed institutional program. In many cases, it is anticipated that the proposed program will complement other ongoing research training programs occurring at the applicant institution and that a substantial number of program faculty will have active research projects in which participating trainees may gain relevant experiences consistent with their research interests and goals.
The PD(s)/PI(s) should be an established investigator in the scientific area in which the application is targeted and capable of providing both administrative and scientific leadership to the development and implementation of the proposed program. The PD(s)/PI(s) will be responsible for the selection and appointment of Scholars to the approved career development program and for the overall direction, management, administration, and evaluation of the program. The PD(s)/PI(s) will be expected to monitor and assess the program and submit all documents and reports as required. The PD(s)/PI(s) has responsibility for the day-to-day administration of the program and is responsible for appointing members of the Advisory Committee, using their recommendations to determine the appropriate allotment of funds. The PD(s)/PI(s) will be expected to monitor and assess the program and submit all documents and reports as required.
The PD(s)/PI(s) are expected to have independent R01 and/or R01-equivalent cancer-focused grant support at the time of application and award. For the NCI K12, R01 or R01-equivalent awards (https://grants.nih.gov/grants/glossary.htm#R01EquivalentGrant) are defined as grants or contracts of at least 3 years in duration and $150,000 per year in direct costs, including those supporting clinical trials.
Direct costs are limited to $50,000 in the initial year of new (Type 1) programs and may be used for curriculum planning and development, advertising, and recruiting of the first class of Scholars. K12 Scholars will begin work in the second year of the grant, where costs are limited to $750,000 direct costs annually. For renewal (Type 2) applications, the program may request up to $750,000 direct costs annually in each of the 5 years.
Funds may be used only for those expenses that are directly related to and necessary for the career development of K12 Scholars and must be expended in conformance with OMB Cost Principles and the NIH Grants Policy Statement.
The award budget includes salary support for the PD(s)/PI(s) and Scholars, research and development support, and administrative support costs.