Paul G. Allen Frontiers Group -- Allen Distinguished Investigator (ADI) Initiative -- Organelle Communication

Funding Agency:
Paul G. Allen Family Foundation

The Paul G. Allen Frontiers Group is announcin a 2024 Allen Distinguished Investigator (ADI) initiative to support research that will elucidate new biological principles associated with inter-organelle communication via membrane-membrane contact sites. Up to three awards will be made for up to $4.5 million in total funding for the initiative.

We seek a set of creative proposals that elucidate new perspectives on inter-organelle communication via membrane-membrane contact sites, with a focus on discovering new biological principles in these interactions. Such new perspectives on membrane contact sites include exploration of new fundamental biological functions and mechanisms of action (e.g., via metabolic compartmentalization), and functional characterization of dynamic changes in membrane contact sites in time and intracellular space (e.g., mechanisms of regulation, coordination, and integration with other cellular processes and components). 

Letters of Intent (LOIs) are due by noon Pacific Time February 14, 2024. Selected LOIs will be invited to submit full proposals to be considered for an ADI award in 2024.

Agency Website

Eligibility Requirements

US or international scientists associated with eligible research organizations and pursuing independent research (e.g., faculty or similar positions) are eligible to apply. Allen Institute employees, fellows, Scientific Advisory Council (SAC) members or advisors are not eligible to apply during their tenure at the Allen Institute. Individuals, including project PIs, co-investigators, and collaborators, receiving support from the Paul G. Allen Family Foundation are not eligible to be part of applications while their award is active. No-cost extension periods are part of active awards. Collaborative teams are welcome; all team members must be associated with eligible research organizations. Eligible research organizations are nonprofit institutions with current 501(c)(3) Public Charity status from the Internal Revenue Service (IRS), non-federal government entities, IRS-recognized tribes, and other organizations that conduct charitable activities. Applicants may not be private foundations as defined in Section 509(a) of the Internal Revenue Code. We ask that, if awarded, the leader commit a minimum of 20% effort to the ADI research activities. We believe that diverse perspectives are vital to science. We encourage researchers from across career stages, who are members of underrepresented groups, and/or who have followed less-traditional career paths to apply. 



Amount Description

 Awards will be $1,500,000 for three years, at the rate of $500,000 per year. 

Funding Type



Junior Faculty
Minorities encouraged


Medical - Basic Science

External Deadline

February 14, 2024