Pediatric Centers of Excellence in Nephrology (P50 Clinical Trial Optional)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) invites applications for the Pediatric Centers of Excellence in Nephrology (PCEN) to support basic, translational and clinical research in pediatric kidney disease. The goals of this program are: 1. to attract new scientific expertise to the study of human pediatric renal physiology, kidney development, and pediatric kidney disorders; 2. to encourage multidisciplinary research in these areas; and 3. to develop the pediatric nephrology research community through a national research symposium, broad sharing of research resources, and a national Pilot and Feasibility grant program. These efforts are expected to lead to innovative approaches to study kidney disease in children and the eventual submission of substantial, competitive, investigator–initiated research applications. The PCEN will complement the O’Brien Kidney and Urological Research Centers and are expected to leverage existing institutional resources which may include Clinical Translational Science Awards, Institutional Network Awards for Promoting Kidney, Urologic, and Hematologic Research Training (U2C/TL1), and other NIDDK-Division of Kidney, Urologic and Hematologic Diseases (KUH)-funded consortia.

Only one application per institution is allowed.


  • Duke Internal: Interested applicants from within Duke should contact as early as possible.
  • Letter of Intent Due Date(s): October 18, 2021

  • Application Due Date: November 18, 2021

RFA-DK-21-024 Expiration Date November 19, 2021

Agency Website

Eligibility Requirements

The PCEN Director must be an established investigator with demonstrated research accomplishments and prior success in obtaining external funding.

Amount Description

The direct costs for the P50 award are expected to be approximately $500,000 per year (excluding Opportunity Pool). Applicants may request $125,000 or more per year for the Opportunity Pool to fund the Pilot and Feasibility program. All Opportunity Pool costs are inclusive of any F&A for the Center and the subawardees. As such, the Center should not calculate F&A on the Opportunity Pool set aside.

Funding Type





Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

November 18, 2021