Sponsor Deadline
Posted: 3/20/2024

Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)

The purpose of this funding opportunity announcement (FOA) is to solicit applications for pilot projects to elucidate a role for understudied proteins associated with rare diseases. Awards will support generation of preliminary data and/or tools around eligible understudied protein(s). A list of eligible proteins is provided and are members of druggable protein families that have a known association with a rare disease. This FOA is intended to jumpstart research on understudied proteins that are associated with rare diseases and provide applicants with sufficient funding to perform basic biochemical and/or biological work to further the characterization of understudied proteins associated with rare disease.


  • Letter of Intent Due Date(s): 30 days prior to the application due date
  • Application Due Date(s): Oct. 17, 2022; March 15, 2023; July 17, 2023; Jan 16, 2024; July 15, 2024

RFA-TR-22-030 Expiration Date July 16, 2024

Amount Description

Application budgets are limited to $100,000 in direct costs (excluding subcontract F&A) for one year and need to reflect the actual needs of the proposed project.

Funding Type
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