LOI Deadline
Posted: 1/6/2025

Prader-Willi Syndrome Research Grants

The Foundation for Prader-Willi Research (FPWR) is dedicated to supporting research to advance the understanding and treatment of Prader-Willi syndrome (PWS).  We invite applications for funding on an annual or semiannual basis, in response to a Request for Applications.

FPWR accepts applications in all areas of research relevant to PWS, but we are particularly interested in supporting projects that will lead to new interventions to alleviate the symptoms associated with PWS.  A more detailed description of FPWR’s funding priority areas is available.

FPWR accepts applications from academic, government, non-profit or for-profit research entities.  Academic research applicants should have a primary faculty appointment at the level of Instructor or higher.  This grant program will be useful for junior faculty in the early stages of their careers, established investigators in other areas of research who wish to enter the field of PWS research, or investigators in the PWS field who are seeking funding to support pilot studies in a new area of PWS research. FPWR seeks to support innovative, high-risk/high reward research in its early stages.

Deadlines​:

Spring 2025

Letters of Intent due February 28th, 2025

Proposals due May 16th, 2025

Fall 2025

Letters of Intent due September 5th, 2025

Proposals due November 14th, 2025

Areas of Interest

Priority will be given to the following areas of research, although alternative areas of high scientific merit will also be considered:

  • Genotype to phenotype: understanding PWS genetics / how loss of PWS-critical region genes leads to the phenotype
  • Neurobiology of hunger / feeding behavior in PWS
  • Neurobiology of cognitive deficits, maladaptive behavior and mental illness in PWS
  • Clinical care research: evaluation of existing drugs and interventions to improve health and quality of life in PWS
  • Therapeutics development for PWS- Genetic therapies; novel pharmaceuticals; drug repurposing for PWS
Eligibility Requirements

 Principal Investigators must have a primary faculty appointment at the level of Instructor or higher.  This grant program will be useful for junior faculty in the early stages of their careers, established investigators in other areas of research who wish to enter the field of PWS research, or investigators in the PWS field who are seeking funding to support pilot studies in a new area of PWS research. FPWR seeks to support innovative, high-risk/high reward research.

Amount Description

Applicants may request up to $100,000 USD in direct costs for the initial year of support, with the possibility of a second year of funding upon competitive renewal.  Indirect costs of up to 8% are allowed.