Sponsor Deadline
Posted: 4/18/2022

Predictive Intelligence for Pandemic Prevention Phase I: Development Grants (PIPP Phase I)

This solicitation is for Development Grants as part of NSF’s new Predictive Intelligence for Pandemic Prevention (PIPP) initiative. This initiative focuses on fundamental research and capabilities needed to tackle grand challenges in infectious disease pandemics through prediction and prevention. NSF anticipates releasing a Phase II Center Grants solicitation around 2023. Note that submission or award of a Development Grant is not required to participate in the anticipated PIPP Phase II Center Grants competition.

The PIPP Phase I initiative intends to support planning activities encompassing (1) articulation of a grand challenge centered around a critical and broad question in pandemic predictive intelligence; (2) proposals of novel conceptual research and technology developments that aim to advance state-of-the-art forecasting, real-time monitoring, mitigation, and prevention of the spread of pathogens; and (3) multidisciplinary team formation. Successful Phase I proposals must identify an innovative interdisciplinary grand challenge that engages integrated computational, biological, engineering, and social/behavioral approaches to formulate and solve critical problems relating to predictive intelligence for pandemic prevention. PIs of Phase I Development Grants are strongly encouraged to develop research and technical approaches that start to address critical aspects of the identified grand challenge.

NSF’s PIPP activities place great emphasis on high-risk/high-payoff convergent research that has the potential for large societal impact. To that end, prospective principal investigators (PIs) must develop teams and proposals that work across scientific, disciplinary, geographic, and organizational divides, push conceptual boundaries, and build new theoretical framings of the understanding of pandemic predictive intelligence.

The Directorates for Biological Sciences (BIO), Computer Information Science and Engineering (CISE), Engineering (ENG), and Social, Behavioral and Economic Sciences (SBE), are jointly collaborating to support the PIPP Phase I activities. Involvement of and collaboration with other research communities with significant effort in related spaces is highly encouraged.

Full Proposal Deadline Date: October 1, 2021

Eligibility Requirements

Proposals may only be submitted by the following:

  • Institutions of Higher Education (IHEs) - Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of subawards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus.
  • Non-profit, non-academic organizations: Independent museums, observatories, research labs, professional societies and similar organizations in the U.S. associated with educational or research activities.
  • Minority Serving Institutions (MSIs) are encouraged to apply.

Proposing teams should demonstrate, among the PIs and co-PIs, balanced participation from computer and information science, biology, engineering, and social, behavioral, and economic sciences as relevant to the identified Grand Challenge problem.

An individual may be designated as PI or co-PI on at most one project team submitting to this solicitation. In the event that an individual exceeds this limit, proposals will be accepted based on earliest date and time of proposal submission, i.e., the first proposal involving that individual as a PI or co-PI will be accepted, and the remainder will be returned without review. No exceptions will be made.

If a proposal involves multiple organizations, it must be submitted as a single proposal with subawards: separately submitted collaborative proposals are not permitted and will be returned without review.

Amount Description

Estimated Number of Awards: 25 to 30

Up to a total of $25 million is available in FY 2022 for 25-30 eighteen-month PIPP Phase I Development Grants.

Anticipated Funding Amount: $25,000,000

Estimated program budget, number of awards and average award size/duration are subject to the availability of funds.