PREventing EMerging Pathogenic Threats (PREEMPT)

Funding Agency:
Defense Advanced Research Projects Agency

DARPA is soliciting innovative proposals for research to develop new tools and models to quantify the likelihood of a virus to jump from an animal host into humans, and to develop and validate new scalable technologies to target potential human-capable viral pathogens in wild reservoirs and/or mosquito vectors to prevent transmission to humans.


  • Proposal Abstract Due Date and Time – February 13, 2018 
  • Proposal Due Date and Time – March 27, 2018 

Agency Website

Areas of Interest

PREEMPT research objectives are structured along two Technical Areas (TAs). Both Technical Areas must be performed in parallel by vertically integrated, interdisciplinary teams. Proposers must present a plan to address both Technical Areas and meet key milestone decision points that occur at the end of year 2.

1) TA1: Develop and validate integrated, multiscale models that quantify the likelihood a human-capable virus will emerge from an animal reservoir residing in a “hot spot” geographic region.

2) TA2: Develop scalable approaches that target and suppress the animal virus in its reservoir(s) and/or vector(s), to reduce the likelihood of virus transmission into humans.

Amount Description

Multiple awards are possible. The amount of resources made available under this BAA will depend on the quality of the proposals received and the availability of funds.

Funding Type





Environmental & Life Sciences
Medical - Basic Science
Medical - Clinical Science

External Deadline

March 27, 2018