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The purpose of the Reach Grant is to advance ALSF’s mission to find cures and better treatments for childhood cancers by providing support to move hypothesis-driven research into the clinic. Significant barriers exist that impede the translation of innovative and important ideas to the clinic. The Reach Grant seeks to remove one of these barriers by providing support for important preclinical projects that are necessary to move a study from the pre-clinical arena into a clinical trial. Thus, the goal of this award is to support selected late-translational studies. Preference will be given to those research projects which, if funded, will likely result in the initiation of a clinical trial in two to three years from the start of the project, by, for example, completing IND-enabling studies, providing requisite preclinical data for clinical trial development, or perhaps through the validation of biomarkers that will enable selection of the correct patients for entry into new clinical trials.
Deadline: March 22, 2021
• Applicants must have an MD, PhD, or MD/PhD or equivalent and be appointed as faculty (or equivalent) at an academic institution.
• Applicants must have a demonstrated track record of pediatric cancer research with experience in translational research.
• Multiple investigator applications that bring together pairs or teams of researchers with complementary expertise are encouraged.
• Applicant institutions may be based in the United States or Canada, and applicants need not be United States citizens. Funds must be granted to nonprofit institutions or organizations
The requested budget should be in proportion to the scope of the proposed project and should be at or under $250,000 USD in direct costs over two years. ALSF does not pay indirect costs for this grant program. A maximum of $125,000 in total costs may be requested per year.