Regional Partnership Grants to Increase the Well-Being of, and to Improve the Permanency Outcomes for, Children and Families Affected By Opioids and Other Substance Abuse

Funding Agency:
Department of Health and Human Services

NOTE: This is a Forecasted Opportunity.

The purpose of this Notice of Funding Opportunity (NOFO) is to provide competitive grant funds for Regional Partnership Grants (RPGs) to improve the well-being of, and to improve the permanency outcomes for children and families affected by opioids and other substance abuse. These targeted grants will be awarded to regional partnerships that provide, through interagency collaboration and integration of programs and services, activities and services that are designed to increase the well-being of, improve permanency outcomes for, and enhance the safety of children who are in out-of-home placements or are at risk of entering out-of- home placements as a result of a parent's or caretaker's substance abuse. Applicants are expected to have a collaborative structure in place that is capable of building a region’s capacity to meet a broad range of needs for families involved with both substance abuse treatment and the child welfare system. Per the legislative requirements, RPGs are required to select and report on performance indicators and evaluation measures to increase the knowledge that can be gained from the program. Partnerships will: use specific, well-defined, and evidence-based programs that are also trauma-informed and targeted to the identified population; conduct an evaluation that is sufficiently rigorous to contribute to the evidence base on service delivery, outcomes and costs associated with the project's chosen interventions; and participate in the national cross-site evaluation, which includes, but is not limited to an implementation and outcomes study. This project is for one 60-month project period, which includes a one-year Planning Phase and a 4-year Implementation Phase. Recipients should anticipate spending no more than $250,000 in the one-year Planning Phase and approximately one-fourth of the remaining project award per each 12-month period of the Implementation Phase.



Estimated Post Date: Mar 21, 2022
Estimated Application Due Date: May 20, 2022

Agency Website

Eligibility Requirements

Applications must identify a primary applicant responsible for administering the grant. The primary applicant MUST be one of the regional partnership organizations listed here. As required by the legislation, regional partnership means a collaborative agreement (which may be established on an interstate, state, or intrastate basis) entered into by at least two of the following parties: the state child welfare agency that is responsible for the administration of the state plan under title IV-B or title IV-E of the Social Security Act and the state agency responsible for administering the substance abuse prevention and treatment block grant provided under subpart II of part B of title XIX of the Public Health Service Act (42 U.S.C. Section 300x-21 et seq.) MUST be included in the partnership; Juvenile Court or Administrative Office of the Court that oversees the administration of court programs that address the population of families who come to the attention of the court due to child abuse or neglect (MUST be included in the partnership if the grant will serve children in out-of-home placement); an Indian Tribe or tribal consortium; non-profit or for-profit child welfare service providers; community health service providers; substance abuse treatment providers; community mental health providers; local law enforcement agencies; school personnel; tribal child welfare agencies or a consortia of the agencies; or any other providers, agencies, personnel, officials, or entities that are related to the provision of child and family services under a state plan approved this subsection. Please refer to the authorizing legislation for additional specifications on the eligibility and requirements of a regional partnership. Eligibility for this funding opportunity is based strictly on the authorizing legislation - Title IV, part B, subpart 2 - Promoting Safe and Stable Families, section 437(f) of the Social Security Act (42 U.S.C. 629g(f)). Applications from individuals (including sole proprietorships) and foreign entities are not eligible and will be disqualified from competitive review and from funding under this funding opportunity announcement. Faith-based and community organizations that meet the eligibility requirements are eligible to receive awards under this funding opportunity announcement.

Amount Description



Funding Type





Community Outreach and Engagement
Medical - Clinical Science
Medical - Translational
Social Sciences

External Deadline

May 20, 2022