The National Cancer Institute (NCI) is seeking input on the use and reuse of cancer metabolomics data. Review of this entire RFI notice is encouraged to ensure a comprehensive response is prepared and to have a full understanding of how your response will be used.
The NCI is seeking input on best practices for cancer metabolomics data storage, management, and use/reuse. Progress in cancer research requires that data is generated via rigorous methods and reported in a complete and transparent way, both to facilitate reproducibility and allow opportunities for reuse in secondary analyses. In alignment with both FAIR (Findable, Accessible, Interoperable, and Reusable) principles and the new NIH policy for Data Management and Sharing (NOT-OD-21-013), a thoughtful assessment of how to address the data management needs of the cancer metabolomics community is critical and timely. Deposition of and access to metabolomics datasets and related code in a way that safeguards the privacy of de-identified clinical data, supports reproducibility, and provides for reuse and harmonization across datasets, particularly in the context of multi-omics and high-throughput integrative analyses, will expand the utility of these data and maximize NIH investments in this area.
This RFI is intended to assist NCI in identifying, developing, and implementing strategies that will speed progress in cancer metabolomics by ensuring that data generated by funded projects is accessible and maximally useful to the entire cancer research community. This RFI invites participation from stakeholders across the cancer research, metabolomics, and data management fields.
All responses must be submitted electronically on the submission website.
Responses must be received by 11:59:59 pm (ET) on December 23, 2022,
NOT-CA-23-007