Research and Development of Vaccines and Monoclonal Antibodies for Pandemic Preparedness (ReVAMPP) Centers for Bunyavirales, Paramyxoviridae and Picornaviridae (U19 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) solicits applications to participate in the Research and Development of Vaccines and Monoclonal Antibodies for Pandemic Preparedness (ReVAMPP) Network. The purpose of this FOA is to establish comprehensive, cooperative basic and translational research Centers to carry out in-depth research on prototype members of select virus families that have the potential to emerge as pandemic pathogens. The goal of these Centers will be to develop vaccine and monoclonal antibody strategies for prototype pathogen(s) that can be applied to closely related family members based on shared functional and structural properties.  This FOA solicits for centers proposing research on virus families from Bunyavirales, Paramyxoviridae and Picornaviridae to be part of the ReVAMPP Network. 

The ReVAMPP Network is comprised of ReVAMPP Centers from both this RFA (Bunyavirales, Paramyxoviridae and Picornaviridae) and its companion FOAs soliciting for ReVAMPP Centers focusing on Flaviviridae and Togaviridae (see RFA-AI-23-019) and the ReVAMPP Coordinating and Data Sharing Center (CDSC) (see RFA-AI-23-021).  ReVAMPP Centers will conduct independent research project(s) and are expected to share information and collaborate within the Network under the direction of the ReVAMPP CDSC which is responsible for establishing and maintaining a collaborative ReVAMPP Network platform for data sharing and overall collaboration among the ReVAMPP Centers. 


  • Letter of Intent Due Date(s): 30 days prior to the application due date

  • Application Due Date: June 8, 2023

RFA-AI-23-020 Expiration Date June 09, 2023

Agency Website

Eligibility Requirements

Applicants listed as a PD(s)/PI(s) for this FOA will not be eligible to be listed as PD(s)/PI(s) on applications submitted to the companion FOA (RFA-AI-23-019) ReVAMPP Centers for Flaviviridae and Togaviridae but can participate as collaborators on subcomponents of those Centers. Applicants to this FOA will not be eligible to submit to or participate in the companion ReVAMPP CDSC FOA (RFA-AI-23-021) due to the centralized role of the CDSC in the Network coordination and communication.



Amount Description

Application budgets are not expected to exceed $10M direct costs/year and need to reflect the actual needs of the proposed project. 

The scope of the proposed project should determine the project period. The maximum period is 5 years.   

Funding Type





Medical - Basic Science
Medical - Translational

External Deadline

June 8, 2023